TED Business is built around a two-part format: a TED Talk followed by host Modupe Akinola's mini-lesson on how to apply the idea at work. Akinola, a Columbia Business School professor, frames each talk around a concrete workplace problem — how to listen better in one-on-ones, how to introduce yourself in twenty words to get hired, how to keep a team unstuck. Recurring themes include workplace communication, career development, leadership and management, and practical frameworks presented as fill-in-the-blank tools listeners can reuse. Alongside these original segments, the feed regularly carries full interview episodes cross-posted from other shows in the TED Audio Collective, which broadens the subject matter well beyond core business topics. Those crossover episodes have covered a solar-irrigation entrepreneur pitching climate tech to investors in Nairobi, a Bloomberg finance writer explaining money and market abstractions, a palliative care physician and disability advocate discussing disability as a social construct, and a journalist-author profile built around a career built on curiosity. Guests are typically subject-matter professionals — consultants, entrepreneurs, physicians, and authors — rather than celebrities. The show suits listeners who want short, applied business and career lessons rather than long-form business news or deep company analysis. Production leans on TED's standard talk-plus-commentary structure for original episodes, with occasional longer, interview-style episodes when content is shared from partner shows. Episode length varies widely as a result, from about 12 minutes for a mini-lesson episode to over 80 minutes for a cross-posted long-form interview.