You Up with Nikki Glaser

You Up with Nikki Glaser is a daily stand-up-adjacent diary where the personal update is usually just the doorway into something messier. Nikki Glaser talks from cars, bedrooms, her dad’s office, late-night post-debate fatigue, and the narrow gaps between appointments and work calls. The show has the intimacy of a running text thread and the volatility of a comedian testing every uncomfortable thought for laughs. Dating apps become a privacy problem within minutes. A Bumble profile leads to screenshots, DMs, paranoia, hope, and the strange comfort of remembering that other single people exist. Politics appears through stress reactions more than analysis: fast eating during a debate, family commentary, and disbelief at the spectacle. Career updates land the same way. Pitch meetings, unnamed television work, Google alerts, and celebrity cameos all become material for anxiety, self-assessment, and jokes about needing a decision to be made for her. The show is also unusually open about mood, medication, depression, addiction reading, and the small routines that make a day survivable. Those moments can be stark. Then a friend enters, a tangent opens, and the episode snaps back into comic motion. Andrew Collin brings late-night banter and family-adjacent riffing. Carlisle Forrester brings friend chemistry, physical comedy talk, and steadier support. Parents, exes, radio calls, runs, documentaries, social media, sex, work ambition, and spiritual curiosity all recur as parts of the same ongoing self-portrait. The show suits listeners who like comedy that feels current, over-caffeinated, candid, and emotionally porous. Its strongest moments come when embarrassment is not cleaned up for presentation. It is examined while still happening.