Up and Vanished is an investigative narrative true crime podcast from Tenderfoot TV, hosted by Payne Lindsey, with each season devoted to a single missing-persons cold case. The current season investigates the disappearances of Joseph Balderas and Florence Okpealuk from Nome, Alaska, tracking leads such as a disputed truck sighting, a wiped phone, an anonymous tip line, and a live-broadcast polygraph test. Episodes mix formats: scripted narrative recaps of case developments, unedited audio of phone calls and interviews, and occasional panel or interview segments with other investigators. Recurring subjects include the missing individuals' family members and witnesses, along with agencies like the FBI and Alaska State Troopers whose conclusions the families dispute publicly. A consistent theme is the friction between public attention surfacing new leads and the podcast's coverage generating legal threats, harassment claims, and privacy disputes for the people involved. The show doubles as a promotional hub for Tenderfoot TV's wider slate, running trailers and crossover episodes for sister podcasts including Status Untraced (hosted by Liam Luxon), High Strange (Lindsey's UFO-investigation spinoff), and Murder True Crime Stories (with host Carter Roy). Another recurring thread is the craft and ethics of true crime podcasting itself, discussed directly in panel conversations with other independent investigators such as Dennis Cooper and Kyle Tekiela. Main narrative episodes run roughly 25 to 55 minutes, while crossover and promotional episodes are often under 10 minutes. The show suits listeners already invested in the franchise's history, including earlier seasons like the Tara Grinstead case, who want incremental case updates rather than closed-ended stories. Production leans on primary-source audio alongside narration, giving it a more procedural, in-progress feel than fully scripted true crime series.