StemCells@Lunch Digested

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Stem cell science, explained from the lab.

The gist

StemCells@Lunch Digested pairs King's College London moderators with stem cell and regenerative medicine researchers after their talks. The conversations translate technical work into plain language while keeping the scientific detail intact.

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About StemCells@Lunch Digested

StemCells@Lunch Digested is built around conversations with researchers connected to stem cells, developmental biology, regenerative medicine, and disease modeling. The setting is academic and practical. A moderator from King's College London’s Centre for Stem Cells and Regenerative Medicine introduces a guest, asks for the shape of the lab’s work, and then slows down the technical material enough for a wider scientific audience to follow. The show does not strip away the science. It keeps words like organoids, microenvironment, histones, telocytes, stem cell niche, metastasis, and ALS in play, then gives them context. Recent episodes move from mini-guts and high-resolution imaging to cancer cells traveling as groups through molecular connections. They look at how organs acquire design principles, how germ cells reset a life cycle, and how stem cell models help researchers study motor neuron disease. The conversations are often most useful when they discuss methods. Guests explain why in vitro model systems changed developmental biology, why microscopy has become more powerful, and why simple models still need enough biological reality to matter. The show also has a second lane: how scientific careers are actually lived. Guests talk about using a PhD as a platform, dealing with failure, learning grant and interview skills, following data into unfamiliar fields, and staying persistent when experiments refuse to work. Career advice appears naturally, not as a separate lecture. The pace is calm and seminar-like. Questions are respectful, answers are detailed, and the show assumes curiosity rather than prior mastery. It is especially strong for students, early-career researchers, and science-minded listeners who want to hear how discoveries are framed by the people doing the work. Stem cell research here feels less like a headline and more like a set of hard, fascinating problems being worked through one careful experiment at a time.

Made for: Best suited to biology students, early-career researchers, science educators, and curious listeners who want careful explanations of stem cell and regenerative medicine research. It also serves anyone considering a research career and looking for realistic accounts of lab life.

What sets it apart: The show pairs seminar-level research with plainspoken follow-up questions from King's College London moderators. It stands out by treating methods, models, career choices, and scientific uncertainty as part of the same story.

In their own words

Keeping the public up to date with current research taking place in the stem cell research community. Listen to guest speakers discuss their work, how they got to where they are today and their hopes for the future of stem cell research. Hosted by King's College London Centre for Stem Cells & Regenerative Medicine.

Why you'd press play

Molecular Velcro holds spreading cancer cells together, if that's your idea of a good rabbit hole.

Press play if you want

  • to hear why a strange result that repeats deserves a closer look
  • to picture how mini guts let researchers watch cell signals change
Read the full recommendation in PlayNext →
stem cell biologyorganoids and in vitro modelsdevelopmental biologycancer cell communicationgerm cells and epigeneticstissue design principlesALS and motor neuron diseaseresearch careers and training

Talks about

Best episodes of StemCells@Lunch Digested

Short reviews from the PlayNext desk, based on the episodes we processed.

Episode 152: Prof Andrew Ewald "Understand the simple rules generating apparent complexity"Apr 25, 2022

A physics-trained cancer biologist searches for simple rules behind metastatic cell behavior.

Professor Andrew Ewald brings a physicist's eye to cancer biology, describing cells as signal-reading, protein-studded actors that can move through the body in small groups held together by molecular Velcro.

Episode 148: Dr Allison Bardin- “Unexpected results lead to novel discoveries”Nov 26, 2021

A stem-cell researcher argues for following strange results until they reveal what the system is doing.

Dr. Alison Bardeen frames adult stem-cell research around a useful scientific instinct: when strange results keep showing up, they deserve attention.

Podcasts like StemCells@Lunch Digested

Episodes

  1. 1

    Episode 153: Dr Ina Sonnen "It is possible to have a career and a family in science"

    Hidden gem

    Stem Cells at Lunch Digested host Jean-François Darigrand interviews Dr.

    Nov 18, 2022·25m·1 clip
  2. 2

    Episode 152: Prof Andrew Ewald "Understand the simple rules generating apparent complexity"

    Hidden gem

    Andrew Ewald says many tumors are cleared by the immune system before diagnosis, but clinically detected cancers can use the microenvironment and natural killer cells to survive.

    Apr 25, 2022·24m·1 clip
  3. 3

    Episode 151: Dr William Roman "Use your PhD as a platform"

    Hidden gem

    William Romain traces a research path from McGill University and a Paris–Berlin MyoGrad PhD to muscle studies in Barcelona, Lisbon, and Stanford.

    Feb 27, 2022·17m·1 clip
  4. 4

    Episode 150: Prof Shalev Itzkovitz "We can infer the design principles of organs"

    Hidden gem

    Dr Shalev Isakovich says intestinal enterocytes can change about 90% of their genes as they move from the crypt to the villus tip over roughly four days, and RNA alone can miss where proteins actually peak.

    Jan 30, 2022·29m·2 clips
  5. 5

    Episode 149: Professor Xin Chen-“We are very fascinated by this kind of ‘immortality’ of germ cells”

    Hidden gem

    In Episode 149 of StemCells@Lunch Digested, Professor Xin Chen explains how epigenetic regulation shapes adult stem-cell behavior.

    Dec 6, 2021·16m
  6. 6

    Episode 148: Dr Allison Bardin- “Unexpected results lead to novel discoveries”

    Hidden gem

    Dr.

    Nov 26, 2021·16m·1 clip
  7. 7

    Episode 148: Dr Allison Bardin- “Unexpected results lead to accidental discoveries”

    Nov 24, 2021·16m
  8. 8

    Episode 147: Professor Yukiko Yamashita- “Junk DNA may not be all Junk”

    Yukiko Yamashita links ribosomal-DNA repeats to germ cells restoring rDNA copy number across generations through chromatid segregation.

    Nov 24, 2021·16m·1 clip
  9. 9

    Episode 145: Prof Elena Ezhkova- “The more you try understand science the more interesting it gets”

    Nov 8, 2021·16m
  10. 10

    Episode 146: Prof Ludo Van Den Bosch– “Exciting time for researchers”

    Nov 8, 2021·15m
  11. 11

    Episode 143 -Prof Denis Duboule - "As long as people are happy in your lab, it's fine"

    Oct 15, 2021·15m
  12. 12

    Episode 144- Prof Filipe Pereira- "It's about defining what will keep you fueled for years"

    Oct 15, 2021·19m
  13. 13

    Episode 142 -Prof Dagmar Iber- "Don't play too safe and be lucky."

    Jul 20, 2021·11m
  14. 14

    Episode 141 - Dr Vikas Trivedi - “You get to learn things from people that you would not know”

    Jul 13, 2021·19m
  15. 15

    Episode 140- Dr Emma Rawlins "I'll look at stem cell in any systems"

    Jul 6, 2021·22m
  16. 16

    Episode 139 - Dr Vanessa Ribes - “We make bonds in thinking and developing ideas”

    Jun 29, 2021·19m
  17. 17

    Episode 138 - Dr Carla Mulas - "Beyond mapping cell states and identities"

    Jun 22, 2021·11m
  18. 18

    Episode 137 - Dr Kristina Haase - "These vessel systems are so beautiful!"

    Jun 8, 2021·14m
  19. 19

    Episode 136 - Dr. Dominika Dziedzicka- "Differentiation propensity"

    May 23, 2021·17m
  20. 20

    Episode 135 - Ieva Berzanskyte - "When I started understanding it more I grew fond of it."

    Apr 27, 2021·18m
  21. 21

    Episode 134-Prof Michael Levin-"Learn the best and put them together in your own way"

    Apr 16, 2021·15m
  22. 22

    Episode 133 – Ana Pombo – “Every day I learn something.”

    Apr 9, 2021·18m
  23. 23

    Episode 132 – Nicolas Rivron – “By understanding the embyro, you understand regeneration.”

    Mar 31, 2021·20m
  24. 24

    Episode 131 - Vivian Li - “I felt like the intestine is actually quite a beautiful system.”

    Mar 17, 2021·19m
  25. 25

    Episode 130 - Derk Ten Berge - "It does require some bravery to spend the time to look for that"

    Mar 9, 2021·17m
  26. 26

    Episode 129 - Ana-Maria Cujba - "I think my passion is for organoids."

    Mar 2, 2021·14m
  27. 27

    Episode 128 - Prof Muzlifah Haniffa - "We are going to map the 37 trillion cells in the human body."

    Feb 23, 2021·13m
  28. 28

    Episode 127- Prof Francesco Saverio Tedesco - “Seeing patients gives you the right motivation.”

    Feb 16, 2021·16m
  29. 29

    Episode 126 - Dr Madeline Lancaster - "It was a classic story of scientific serendipity"

    Jan 5, 2021·13m
  30. 30

    Episode 125 - Dr Jürgen Knoblich- “Studying the brain is like studying oneself.”

    Dec 28, 2020·21m
  31. 31

    Episode 125 - Dr Randolph Ashton - "I have faith in the cells, they can do a lot themselves."

    Dec 7, 2020·12m
  32. 32

    Episode 124 - Prof Weiss - "When I realised we could programme cells, I knew it is what I had to do"

    A PhD student interviews a pioneer in synthetic biology about genetically programming cells for stem cell research.

    Nov 25, 2020·23m
  33. 33

    Episode 123 - Prof Manuel Serrano - "Understanding aging can help treat other diseases."

    Nov 17, 2020·14m
  34. 34

    Episode 122- Prof Matthias Lütolf - "Organoids give us a new window into human biology."

    An interview with Matthias Luthoff about his lab's work on using engineering approaches to guide stem cell organoid formation.

    Oct 27, 2020·24m
  35. 35

    Episode 121 - Prof Kevin Eggan - "Science progresses through replication, validation, extension"

    Oct 21, 2020·16m
  36. 36

    Episode 120 - Prof Salvador Benitah - "I still have to sit down and learn new things"

    A PhD student interviews a researcher about their work on how tissues maintain themselves, aging, and cancer development.

    Oct 13, 2020·24m
  37. 37

    Episode 119 - Prof Alfonso Martinez Arias - "The 21st Century is the Century of the Cell."

    An interview with Professor Alfonso Martinez-Arias about his research on how a single cell becomes an organism using embryonic stem cells.

    Oct 9, 2020·20m
  38. 38

    Episode 118 - Prof Trepat - "The biggest questions of our generation are in life sciences"

    Sep 29, 2020·13m
  39. 39

    Episode 117 - Prof Peter Zandstra - "We are bringing technology and biology together"

    Sep 22, 2020·13m
  40. 40

    Episode 116 - Dr William Grey - Are proteins the key to understanding cancer?

    Sep 15, 2020·12m
  41. 41

    Episode 115 - Prof James Briscoe - Where does time come from in development?

    Aug 26, 2020·8m
  42. 42

    Episode 114 - Prof Janet Rossant - "Science is going to get us out of this, science is the answer."

    Aug 19, 2020·16m
  43. 43

    Episode 113 - Prof Olivier Pourquié - "I think pretty much every bit of Biology is interesting."

    Aug 12, 2020·14m
  44. 44

    Episode 112 - Prof Cristina Lo Celso - "At the time stem cells seemed like the holy grail."

    Aug 5, 2020·12m
  45. 45

    Episode 111 - Dr Ivo Lieberam - "How we are going to interact with technology in the long term?"

    Jul 28, 2020·17m
  46. 46

    Episode 110 - Dr Francesca Spagnoli- "We study biological problems with direct medical application."

    Jul 22, 2020·13m
  47. 47

    Episode 109 - Prof James Sharpe - "You were limited by nothing but your own imagination."

    Jul 14, 2020·13m
  48. 48

    Episode 108 - Prof Jianping Fu - “Human development itself is just fascinating.”

    Jun 30, 2020·18m
  49. 49

    Episode 107 - Prof Ludovic Vallier - "The drive is to generate more knowledge."

    Jun 23, 2020·18m
  50. 50

    Episode 106 - Professor Peter Jones - "I think all scientists are curious by nature."

    Jun 16, 2020·11m