Repurposed drugs and rare disease, anchored by a physician scientist's survival story.
Raise the Line uses its sixth anniversary to bring back Dr. David Fagenbaum, the physician scientist whose own survival helped shape EveryCure.

Serious conversations about better health care.
Raise the Line brings clinicians, educators, advocates, and health-policy leaders into careful conversations about improving care. Its strongest episodes connect personal experience to larger systems, from rare disease diagnosis and medication access to AI, clinical training, and public trust.
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Raise the Line is a health-care interview show with a calm, professionally guided center. It is built for depth. Rather than treating medicine as a stream of headlines, it lets clinicians, educators, public health leaders, patients, and advocates explain how care improves or fails in practice. The show is especially strong when a personal story opens onto a larger system. Dr. David Fajgenbaum's work on repurposed medications becomes a conversation about rare disease, feasibility, and finding existing drugs that can save lives. Shanti Hegde's account of living with rare bleeding disorders becomes a window into diagnosis delays, insurance barriers, mental health access, and research equity. Other episodes look at AI in the doctor-patient relationship, precision learning for future clinicians, independent medical practice, public health partnerships, and the science of credible communication. The pace is measured. Questions are often full and contextual, giving guests room to build a chronology before turning toward the lesson. That structure gives the show a useful dual focus: it respects the emotional weight of illness while staying attentive to policy, training, funding, technology, and delivery models. It can be technical without losing the patient. It can be compassionate without becoming vague. The series also returns to the people who carry health care forward, from early career professionals to leaders managing public health strategy or major clinical organizations. Its editorial center is clear: better care depends on better systems, better education, better communication, and a willingness to listen closely to patients. For PlayNext discovery, Raise the Line fits listeners who want substantive medical and public health conversations without sensationalism.
Made for: Suited to clinicians, health students, public health professionals, patient advocates, and policy-minded listeners who want careful conversations about care delivery, education, and innovation.
What sets it apart: Its strength is the bridge between lived experience and systems thinking: rare disease stories, AI strategy, public health communication, and medical practice models are treated as connected problems in health care.
Join host Lindsey Smith and other Osmosis team members for a global conversation about improving health and healthcare with prominent figures in education and healthcare innovation such as Chelsea Clinton, Mark Cuban, Dr. Ashish Jha, Dr. Eric Topol, Dr. Vivian Lee and Sal Khan, as well as senior leaders at organizations such as the CDC, National Institutes of Health, Johns Hopkins University, WHO, Harvard University, NYU Langone and many others.
Based on 6 episodes we listened to · September 2026
Focused interviews connect healthcare innovation to the practical pressures faced by patients, clinicians, educators, advocates, and public health leaders.
Raise the Line turns healthcare improvement into a series of focused interviews, with Lindsay Smith and Michael Kuris moving between patient experience, clinical practice, public health, medical education, and emerging technology.
A $10,000 vial and a doctor facing a screen: your questions about better care get very specific.
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Short reviews from the PlayNext desk, based on the episodes we processed.
Repurposed drugs and rare disease, anchored by a physician scientist's survival story.
Raise the Line uses its sixth anniversary to bring back Dr. David Fagenbaum, the physician scientist whose own survival helped shape EveryCure.
A grounded look at private practice, university medicine, and the tradeoffs between freedom and risk.
This Raise the Line conversation focuses on the business of practicing medicine, using Rothman Orthopedic Institute to set private practice against university employment.
A practical case for building health campaigns around audience, messenger, and story first.
Health communication gets a grounded, practical reading here. Tesfa Alexander, deputy director of the Lerner Center for Public Health Advocacy at the Johns Hopkins Bloomberg School of Public Health, speaks with Lindsay Smith about what makes public health messages land: knowing…
A patient's diagnosis journey gives rare-disease advocacy its human scale.
Rare bleeding disorders become a story about being heard in Raise the Line's conversation with Shanthi Hegde, a national advocate whose own diagnosis journey shapes her work.
A clear account of Rotatech's long path from vaccine research to safety surveillance.
Public trust in vaccines gives this Raise the Line episode its charge. Dr. Paul Offit, pediatrician, scientist, author, and director of the Vaccine Education Center at Children's Hospital of Philadelphia, brings the subject down to the practical level: how vaccine science is…
A measured look at how visual, concentrated learning fits into Elsevier's medical education strategy.
Raise the Line frames David Game's long career in educational technology as a grounded look at how medical students learn today. As Elsevier's Senior Vice President of Product Management for Global Medical Education, Game brings the discussion back to digital strategy and…
A grounded look at AI as a way to give clinicians more room for the human side of medicine.
Raise the Line frames artificial intelligence in medicine around a practical question: whether it can give clinicians more space for the human work patients feel most directly. Dr.

Measured MS science, translated for care.




Clinical research, translated for practice.
Health care evidence with managed care consequences.
Lindsey Smith interviews David Game, SVP of Product Management for Global Medical Education at Elsevier, about his career in educational technology.
Dr.
This episode features an interview with Dr.
This episode features an interview with Lindsay Howard, an experienced NICU nurse, discussing the increasing need for specialization in neonatal intensive care nursing due to advances in medicine and rising NICU admissions.
This episode features brothers Kyle and Brent Pease discussing their journey as the first push-assist brother duo to complete the Ironman World Championship, their advocacy for disability inclusion through sports and employment, and the work of the Kyle Pease Foundation.
This episode explores a research project translating over 100 Osmosis medical education videos into Arabic to improve student engagement, comprehension, and educational equity globally.
Lindsay Smith marks Raise the Line's sixth anniversary by revisiting Dr.
This episode explores how artificial intelligence could strengthen rather than harm the doctor-patient relationship, featuring insights from Dr.
This episode explores how artificial intelligence is transforming healthcare education through precision learning, featuring an interview with Paul Crockett, Chief AI Officer at Elsevier.
This episode features an interview with Dr.
This episode features an interview with Madison Donnelly, a women's health physician assistant, discussing her career journey, medical training, and approach to patient care, particularly for vulnerable populations.
Michael Kuris welcomes Dr.
["Raise the Line with Osmosis interviews Tesfa Alexander about health communication when science and government face mistrust.", "Lindsay Smith introduces Alexander as deputy director of the Lerner Center for Public Health Advocacy at the Johns Hopkins Bloomberg School of Public Health and an associate practice professor.", "Alexander traces his path from painting, airbrushing, and poetry to organizational communication at Emerson College and a first public-health job at the Massachusetts Department of Public Health.", "He uses the FDA's Real Cost campaign, youth-targeted messages about wrinkles and yellow teeth, and trust-building strategies to show how public-health communication changes behavior."]
Shanthi Hegde brings her experience as a rare disease patient into a conversation about advocacy.
Raise the Line host Lindsay Smith interviews Dr.
This episode features parents Eric and Kristi Levine discussing their family's journey with their child's rare genetic disorder CACNA1A, emphasizing the importance of holistic patient care and raising awareness.