Burn it Nutrition Podcast · Joseph Navarro Fitness, Nutrition, Ketogenic, Paleo, Keto, Diet Coach

Ep190: Sex, Energy, Performance: The Untold Power of Nitric Oxide with Dr. Nathan S. Bryan

·50 min·2 clips

Bryan says Viagra-class drugs, FDA-approved in 1998, work in only 50% of men because they don't produce nitric oxide.

1. Burn it Nutrition Podcast Ep190 covers nitric oxide, with Dr. Nathan S. Bryan describing its role in blood pressure, sexual performance, brain function and recovery. 2. Host Joseph Navarro interviews Bryan, who is introduced as one of the world's leading nitric oxide researchers with over 100 peer-reviewed publications. 3. Bryan's thesis is that losing natural nitric oxide production causes high blood pressure, erectile dysfunction and brain fog, and that restoring it treats the root cause instead of adding medications. 4. Bryan traces his interest to a biochemistry degree at the University of Texas at Austin and to Nobel laureate Lou Ignarro, who told him that "if you can figure out how to safely and effectively restore the natural production of nitric oxide," it would change medicine. 5. He cites a 2007 paper showing nitric oxide is a hormone, and a 15-year-old patient at Texas Children's Hospital whose 210 over 115 blood pressure fell to 130 over 80 within four hours, with kidney disease reversed in five days and heart disease in five months. 6. He explains that nitric oxide relaxes smooth muscle in vessel walls, and that with "pressure equals volume times resistance," restoring it lowers pressure; he adds that 50% of people on ACE inhibitors, ARBs, calcium channel blockers or diuretics do not respond. 7. On sexual function, Bryan says PDE-5 inhibitors approved by the FDA in 1998 only prevent the breakdown of cyclic GMP, so the 50% of men who don't respond are not making enough nitric oxide to start the signal. 8. For women, he says estradiol activates nitric oxide production, so perimenopause and menopause bring endothelial dysfunction, and he links libido, lubrication and orgasm to nitric oxide-driven blood flow. 9. He says production falls 10% to 12% per decade from the early 20s, and he blames the "SAD diet," inactivity, antiseptic mouthwash, fluoride and proton pump inhibitors, which he links to a 40% increase in heart attack, stroke and Alzheimer's. 10. His practical steps are non-fluoridated toothpaste, no mouthwash, weaning off antacids, tracking glucose, 18-hour daily fasts, 6 to 8 minutes of HIIT, morning sunlight, leafy greens, 6 to 8 hours of sleep and nasal breathing. 11. Listeners interested in cardiovascular health, sexual performance, fasting and longevity will get the most from it.

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