Grand Rounds follow-ups on dementia and aging research in practice.
NIA IMPACT Collaboratory pairs Grand Rounds webinars with follow-up conversations that give presenters more time to answer questions about their work. The subjects stay practical: Medicare payment for dementia care, training champions inside care homes, adapting trials for Latino participants, and choosing fair sites and outcome measures for large pragmatic trials.
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NIA IMPACT Collaboratory is the podcast companion to the Grand Rounds webinars run by the National Institute on Aging Impact Collaboratory at Brown University. Jill Harrison, an executive director of the collaboratory, sets out the premise at the top of the episodes: more time with the speakers, and the questions an audience would most want answered. The companion Grand Rounds content is at impactcollaboratory.org. The podcast is the follow-up. Who asks the questions varies. Harrison sits down with Julie Bynum, principal investigator Susan Mitchell talks with Clive Ballard, and a University of Colorado professor leads a four-way conversation with three researchers on cultural adaptation. The common ground is aging and dementia care, approached through the practical machinery of pragmatic trials. One conversation is about money. A guest from the CMS Innovation Center explains the GUIDE model's Dementia Care Monthly Payment, a per-member-per-month amount set by severity tier, and ties it to the Innovation Center's priority of moving from fee for service toward value-based care. Support that can be passed through to caregivers is greeted as a long-sought change. Another conversation is about training. The WHELD Programme conversation describes care homes committing staff champions to a run of sessions over 12 weeks, after which those champions mentor colleagues while a digital platform stays open to all staff. Direct training was tried too, and the champion model held up better because it is built into the home itself. Equity comes up across several episodes. Russell Glasgow, of the University of Colorado Anschutz Medical Center, points to dissemination-implementation.org, a web tool for selecting and adapting implementation frameworks that has added a special topics section on health equity. From there the talk moves to which sites a large pragmatic trial recruits from and whether its outcome measures fit. The cultural adaptation episode weighs community advisors' recommendations, some of them set aside to protect study fidelity and saved for the next research application. The Bynum conversation explains why a data resource broken out by race, ethnicity and age is available only through a reviewed request instead of being posted online. Home and community settings get their own episode, with three guests on reading an organization's priorities, winning buy-in, and the harder problem of keeping a program going once those priorities shift. The tone is collegial and appreciative, and conversations close on thanks. For a first listen, 'Podcast 47: The GUIDE Model' suits a policy question, 'Podcast 46: The WHELD Programme' suits an implementation question, and 'Podcast 48: RE-AIM, its PRISM expansion, and their application in pragmatic trials' suits anyone weighing frameworks.
Made for: Suits a listener who plans, funds or runs studies in aging and dementia care and wants the practical follow-ups: payment tiers, fair recruitment, staff training and data access. Also a good fit for someone who watched a Grand Rounds webinar and wants more time with the presenters.
What sets it apart: It is built as a companion to the collaboratory's Grand Rounds webinars, so the conversations work as follow-ups that press on specifics: how a dementia care payment is tiered, how care-home champions are trained, and how equity shapes where a trial recruits.
Podcast by NIA IMPACT Collaboratory
The follow-up call after a biomarker result is exactly the detail you came for.
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Short reviews from the PlayNext desk, based on the episodes we processed.
A practical review of how GUIDE sets out to finance dementia care and caregiver support.
The episode treats the GUIDE initiative as a working policy problem: how dementia care and caregiver support are financed once a model has to operate inside a real healthcare system.
A grounded look at how cultural adaptation can reshape dementia research, while study design still sets firm limits.
This PlayNext single-episode review frames a palliative-care trial for hospitalized dementia patients as a useful look at cultural adaptation for Latino participants.
A grounded discussion of how research has to fit the priorities and financial realities of community organizations.
Embedded pragmatic clinical trials work best when they line up with the priorities of the organizations expected to carry them forward. Cheryl Zimmerman, Ellen McCready, and Tina Sada-Raghani look at how community partnerships shape research engagement, implementation, and…
A practical, measured look at explaining Alzheimer's biomarkers when risk, symptoms, and next steps do not align cleanly.
Clinical implementation is where Alzheimer's biomarkers run into the real work of disclosure, uncertainty, and follow-up. Jill Harrison speaks with Dr. Kyra O'Brien of Penn Memory Center at the University of Pennsylvania and Dr.
Oncology evidence translated into clinical decisions.
Critical care evidence, carefully talked through.
Clinical research, reduced to its practical signal.
Jill Harrison of the NIA Impact Collaboratory asks Russell Glasgow how RE-AIM and PRISM can guide pragmatic clinical trials.
Podcast 47 of the Impact Collaboratory Grand Rounds podcast features Tanya Saffer, Christine Lees-Haggerty, and Gary Epstein-Lebo discussing the CMS Innovation Center’s GUIDE model for dementia care.
The NIA Impact Collaboratory Grand Rounds podcast brings Susan Mitchell into conversation with Dr.
Julie Bynum explains why national averages may not show the needs of a local community when planning dementia studies.
Laura Hansen says the adaptation exposed an "English-speaking exclusion" she now calls a fundamental flaw in research design for dementia trials.
Jill Harrison of the National Institute on Aging Impact Collaboratory at Brown University talks with Cheryl Zimmerman, Ellen McCready, and Tina Sada-Raghani about embedded pragmatic clinical trials in assisted living and adult day services.
["A pilot across seven diverse primary care practices in central Indiana screened symptomatic patients with a digital cognitive assessment, then offered blood biomarker disclosure to 26 of 236 potentially eligible patients.", "Jill Harrison's guests, Kyra O'Brien of Penn Memory Center at the University of Pennsylvania and Nicole Fowler of Indiana University School of Medicine, explain why only about half of primary care providers agreed to disclose results themselves.", "They say PCPs wanted clearer training, decision trees, and referral pathways before using biomarkers in routine care, especially when results must feed into treatment or case-management plans.", "The episode also compares amyloid and tau results, reviews pre-test education and follow-up calls, and warns that direct-to-consumer testing is only appropriate for people who understand the limits and risks."]
Michael Harhey’s NIA Impact Collaboratory discussion examines how death can truncate outcomes in randomized trials.
A podcast episode discussing partnering with people living with dementia and care partners in research, featuring the Empowering Partnerships Project.
A podcast discussing challenges and insights from pragmatic clinical trials in healthcare settings, featuring chief medical officers.
A podcast episode featuring interviews with pilot grant awardees discussing their research in pragmatic clinical trials for older adults.