Clinical updates sorted into practice decisions.
Keeping Current CME turns specialist updates into structured clinical education. Episodes move briskly through disclosures, learning objectives, trial data, biomarker testing, treatment algorithms, and practical implications for patient care.
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Keeping Current CME is a large clinical education feed organized around timely medical decisions. It has the feel of a faculty room rather than a personality-led talk show. Episodes usually open with CME disclosures, learning objectives, and resource notes, then move into the clinical topic with little delay. The format is brisk. Recent programming is heavily clinical and specialty-driven, with sessions on antibody-drug conjugates in metastatic triple-negative breast cancer, oral SERD-based strategies in ER-positive/HER2-negative metastatic breast cancer, biosimilars in primary care, antiseizure medication selection before epilepsy surgery, and erosive esophagitis diagnosis. Oncology appears often. So do biomarkers, treatment algorithms, trial data, first-line and second-line decisions, and patient-selection caveats. The show is comfortable with technical detail, including PD-L1 status, HER2 testing, ctDNA, NGS, IHC, MSI-high disease, CDK4/6 inhibitors, anti-PD-L1 therapy, and HER2-targeted regimens. It also pays attention to practical constraints. Tissue may be insufficient, liquid biopsy may be limited by disease burden and shedding, and treatment duration may be shaped by tolerability. The best use of the format is not broad health advice. It is clinical orientation. Faculty members define the disease state, describe the evidence base, compare options, and keep returning to what a clinician might do next. Some episodes use patient cases, such as persistent heartburn and regurgitation in erosive esophagitis, to anchor diagnostic choices. Others work through new or emerging therapy classes and explain where they may sit in the care pathway. The tone is neutral, occasionally grave, and consistently procedural. It assumes medical fluency. It does not slow down to explain every acronym or mechanism, but it usually gives enough structure for a clinician to follow the decision logic. For PlayNext, the signal is clear: this is a focused CME feed for professionals who want evidence converted into practice steps, not a general-audience medical conversation.
Made for: Keeping Current CME is for clinicians, nurses, and medically fluent listeners who want concise specialty updates tied to CME activity. It best suits listeners comfortable with trial language, biomarkers, therapy sequencing, and regulatory caveats.
What sets it apart: The show stands out for its procedural CME structure: disclosures, objectives, faculty discussion, clinical scenarios, and practice implications. It emphasizes how evidence changes testing and treatment choices rather than treating medical news as commentary.
Hear from experts as they discuss timely clinical topics as well as relevant and actionable strategies for practice improvement. This podcast is available for CME credit.
Based on 6 episodes we listened to · September 2026
Keeping Current CME makes evolving clinical evidence usable by tracing how testing, treatment options, and patient circumstances shape real decisions.
Keeping Current CME turns clinician-led presentations and conversations into close readings of treatment decisions. Its range extends from biomarker testing in lung and colorectal cancers to therapy choices in breast cancer, inflammatory bowel disease, bronchiectasis, and…
A negative liquid biopsy isn't a clean exit; you get the tissue-testing caveat, too.
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Short reviews from the PlayNext desk, based on the episodes we processed.
Monotherapy ADCs, PD-L1 status, and the treatment-line squeeze in metastatic TNBC.
This segment presents metastatic triple-negative breast cancer as a sequencing problem, with about 50% or fewer patients reaching second-line treatment and only 25% to 26% moving on to third line or beyond.
A focused CME update that turns biomarker and trial data into practical colorectal cancer choices.
This episode follows a community-based colorectal cancer CME session on adjuvant and neoadjuvant therapy, with biomarker actionability in stage 3 colon cancer at the center.
A practical review of HER2 testing strategy and treatment uncertainty in HER2-mutated non-small cell lung cancer.
This episode keeps the focus on HER2-mutated non-small cell lung cancer where it matters most in practice: how biomarker testing can guide decisions when PCR, NGS, IHC, tissue, and liquid biopsy do not all point cleanly in the same direction.
A clinically orderly guide to genetic testing, family counseling, and treatment choices in cholestatic disease.
Cholestatic disease is framed as a set of practical clinical decisions: when genetics belongs in the workup, how families should be counseled, and where genotype may shape management.
A practical clinical guide to CT diagnosis, exacerbation risk, tailored treatment, and prevention.
Bronchiectasis is framed as a practical clinical problem: CT anchors the diagnosis, but the ongoing challenge is spotting exacerbations early and tailoring treatment to the patient in front of the clinician.
A brisk guide to matching newer IBD options with disease features, patient factors, and safety.
Newer IBD therapies have broadened the treatment menu, and "Debating New IBD Treatments: Ready, Set, Go!" frames that abundance as a brisk clinical exchange about what comes after anti-TNF loss of response or intolerance. Dr. Russ Cohen and Dr.
A practical review of why recurrent nasal polyps often call for both biological insight and broader treatment planning.
Chronic rhinosinusitis with nasal polyps is treated here as a persistent clinical problem, not a one-time surgical fix. The discussion ties topical and systemic steroids, surgery, steroid delivery systems, and biologics to patients whose disease keeps coming back, with a steady…
Jonquilyn Hill chases one listener question per episode to the experts who can answer it.
Hard conversations, patiently held, with room to laugh.
Fearne Cotton interviews guests like Boy George and Bryony Gordon about mental health and identity.
Dr. Joy Harden Bradford pairs therapy insight with Black TV recaps, maternal health, and history.
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This episode features a discussion between rheumatologist Dr.
Professor Jonathan Barrett and Professor Anjay Rastogi explain why the kidney's glomerular basement membrane, lacking inherent complement inhibitors, is vulnerable to complement-mediated injury in IgA nephropathy.
The host opens on metastatic triple-negative breast cancer as a major unmet need.
This educational program features oncology experts discussing current treatment approaches for ER-positive/HER2-negative metastatic breast cancer, focusing on oral SERD-based therapies and biomarker-driven strategies.
This educational program introduces primary care providers to biosimilars, covering their definition, clinical evidence, and practical strategies for discussing them with patients.
This educational podcast discusses strategies for optimizing antiseizure medication selection to maximize therapeutic efficacy before epilepsy surgery, featuring expert neurologists.
This educational program discusses the evolution of anti-HER2 therapies for treating gastroesophageal adenocarcinoma, focusing on current and emerging first-line treatments for advanced or metastatic cases.
The episode centers on adjuvant and neoadjuvant therapy for colorectal cancer, with the conversation framed around making key biomarkers more useful in a community-based colorectal cancer clinic.
The faculty look at how clinicians can make personalized decisions for patients with HER2-mutated non-small cell lung cancer.
This educational podcast discusses how to identify suboptimally managed erosive esophagitis in clinical practice, focusing on diagnosis and patient cases.
Keeping Current CME uses a community-submitted case to review progressive familial intrahepatic cholestasis, with Tatiana Kushner tying the topic to pruritus and cholestasis.
Anne O'Donnell of Georgetown University frames bronchiectasis as a disease best diagnosed by CT scan, with patterns that can suggest CFTR abnormality, aspiration, or nontuberculous mycobacterial infection.
This episode discusses recent updates in chronic lymphocytic leukemia treatment, focusing on combination approaches presented at ASH 2025, including BTK inhibitors and the CLL17 study.
This educational program discusses recent advances in managing moderate to severe asthma, including biologics and remission goals, while addressing ongoing challenges like treatment adherence and patient partnership.
This educational program reviews cases in narcolepsy and idiopathic hypersomnia, focusing on integrating treatment decisions that prioritize sleep quality and cardiovascular risk.