JAMA Neurology Author Interviews

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Neurology papers, explained by their authors.

The gist

JAMA Neurology Author Interviews offers concise, clinically focused discussions with authors of recent neurology investigations. The tone is formal but accessible, moving from study rationale to design, outcomes, and what neurologists may do next.

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About JAMA Neurology Author Interviews

JAMA Neurology Author Interviews gives neurologic research a direct oral format. The show pairs a structured interviewer with authors of recent JAMA Neurology articles. Episodes usually begin with the clinical problem. Then the conversation narrows. Study design, enrollment criteria, comparator groups, endpoints, and limitations become the real subject. The pacing is academic, but the questions keep the work tied to patient care. Recent episodes spend serious time on stroke medicine, including mechanical thrombectomy, thrombolysis timing, anticoagulation after atrial fibrillation-associated ischemic stroke, and recurrent intracerebral hemorrhage. Migraine care is another recurring lane. Discussions cover fremanezumab for migraine with major depressive disorder and cardiovascular safety questions around anti-CGRP monoclonal antibodies in older adults or adults with disability. The show also reaches into idiopathic intracranial hypertension, where GLP-1 receptor agonists are considered alongside medication use, bariatric surgery, shunting, and optic nerve fenestration. Multiple sclerosis appears through the lens of radiologically isolated syndrome and biomarkers that may help estimate future symptom risk. Huntington disease is treated through a therapeutic question about beta-blocker use and disease onset or progression. The vocabulary is clinical. The aim is clarity. Guests explain why certain populations were included or excluded, why particular scales were chosen, and how methods such as propensity matching or sequential cohort design shape interpretation. The strongest moments come when trial logistics meet real-world medicine, as with delayed study drug starts after thrombolysis or site readiness around anticoagulation timing. It is not a broad wellness program. It is a specialized listen for people who want to hear how neurologists and physician-scientists reason through evidence. The result is closer to an expert journal briefing than a casual medical chat.

Made for: For neurologists, trainees, researchers, and medically fluent listeners who want close readings of clinical neurology studies. It also suits health journalists and evidence-focused clinicians tracking changes in stroke, migraine, MS, and neurodegenerative care.

What sets it apart: The show keeps the article itself at the center, with authors walking through methods, populations, outcomes, and clinical meaning. Its value is the disciplined bridge between peer-reviewed neurology research and bedside decision-making.

In their own words

Interviews with authors of articles from JAMA Neurology. JAMA Neurology is an international peer-reviewed journal for physicians caring for people with neurologic disorders and those interested in the structure and function of the normal and diseased nervous system.

Why you'd press play

A migraine trial brings two depression scales; your inner methodology nerd can take notes.

Press play if you want

  • a stroke researcher to explain what patients received alongside standard care
  • to hear why migraine days and depression were measured separately
Read the full recommendation in PlayNext →
acute ischemic stroke treatmentmechanical thrombectomymigraine therapiesmultiple sclerosis risk markersidiopathic intracranial hypertensionintracerebral hemorrhage recurrenceHuntington disease treatmentclinical trial design

Talks about

Best episodes of JAMA Neurology Author Interviews

Short reviews from the PlayNext desk, based on the episodes we processed.

Intravenous Argatroban or Eptifibatide and Mechanical ThrombectomyAug 18, 2025

A focused look at how stroke-trial design meets the practical pressures of thrombectomy care.

A stroke-treatment question comes into focus where trial protocol meets the clock. JAMA Neurology Author Interviews has Dr. Cynthia Armand speaking with Dr.

GLP-1 Receptor Agonists in Idiopathic Intracranial HypertensionJul 14, 2025

A clinically grounded look at GLP-1 receptor agonists as a possible path in idiopathic intracranial hypertension care.

GLP-1 receptor agonists are framed here as a possible new direction for idiopathic intracranial hypertension, a neurologic condition involving increased intracranial pressure without a structural cause. The episode works best when Dr. Cynthia Armand and Dr.

Optimal Delay Time to Initiate Anticoagulation After AF-Associated Ischemic StrokeMar 31, 2025

A careful look at how stroke severity, hemorrhagic risk, and clinical uncertainty shape anticoagulation timing.

Anticoagulation after ischemic stroke from atrial fibrillation comes down to timing: how soon to treat when hemorrhagic risk, stroke severity, and uncertainty all pull in different directions.

Podcasts like JAMA Neurology Author Interviews

Episodes

  1. 1

    Intravenous Argatroban or Eptifibatide and Mechanical Thrombectomy

    Hidden gem

    Dr.

    Aug 18, 2025·19m·1 clip
  2. 2

    GLP-1 Receptor Agonists in Idiopathic Intracranial Hypertension

    Hidden gem

    JAMA Neurology Author Interviews features Dr.

    Jul 14, 2025·22m·1 clip
  3. 3

    Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome

    Jun 2, 2025·14m
  4. 4

    Fremanezumab for the Treatment of Migraine and Major Depressive Disorder

    Hidden gem

    Fremanezumab reduced monthly migraine days and also lowered HAMD-17 and PHQ-9 scores.

    May 5, 2025·21m·1 clip
  5. 5

    Optimal Delay Time to Initiate Anticoagulation After AF-Associated Ischemic Stroke

    Hidden gem

    Dr.

    Mar 31, 2025·17m·1 clip
  6. 6

    Location and Timing of Recurrent, Nontraumatic Intracerebral Hemorrhage

    Mar 3, 2025·16m
  7. 7

    Cardiovascular Safety of Anti-CGRP Monoclonal Antibodies in Older Adults or Adults With Disability With Migraine

    Jan 6, 2025·18m
  8. 8

    β-Blocker Use and Delayed Onset and Progression of Huntington Disease

    Jordan Schultz reports that Enroll-HD participants taking beta blockers had lower annualized risk of receiving a motor diagnosis in pre-manifest Huntington disease.

    Dec 2, 2024·19m·1 clip
  9. 9

    Alzheimer Disease as a Clinical-Biological Construct

    Giovanni Frisoni argues that Alzheimer's should remain a clinical-pathological diagnosis, not a label based on biomarkers alone.

    Nov 1, 2024·22m·1 clip
  10. 10

    Perceived CTE in Former Professional Football Players

    Among 2,000 former football players surveyed, 35% believed they had CTE, a diagnosis confirmed only after death.

    Sep 23, 2024·17m·1 clip
  11. 11

    Localized Nicardipine Release Implants for Prevention of Vasospasm

    Aug 19, 2024·15m
  12. 12

    Direct-Acting OACs and Antiseizure Medications for AF and Epilepsy and Risk of Thromboembolic Events

    Jul 8, 2024·20m
  13. 13

    Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation

    May 28, 2024·18m
  14. 14

    Association of New-Onset Seizures With SARS-CoV-2 Vaccines

    Apr 29, 2024·17m
  15. 15

    High-Efficacy Therapy Discontinuation vs Continuation in Patients 50 Years and Older With Nonactive MS

    Mar 25, 2024·14m
  16. 16

    Posttraumatic Epilepsy and Dementia Risk

    Feb 26, 2024·13m
  17. 17

    Risk of Stroke and Myocardial Infarction Among Initiators of Triptans

    Feb 5, 2024·11m
  18. 18

    Risk Factors for Young-Onset Dementia in the UK Biobank

    Dec 26, 2023·15m
  19. 19

    Endovascular Therapy Outcomes by ASPECTS and Infarct Core Volume in Patients With Large Infarct

    Nov 27, 2023·14m
  20. 20

    Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis

    Nov 6, 2023·19m
  21. 21

    Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease

    Oct 30, 2023·17m
  22. 22

    Neuropathologic and Clinical Findings in Athletes With Repetitive Head Impacts

    Aug 28, 2023·17m
  23. 23

    Dementia Risk and Disadvantaged Neighborhoods

    Jul 19, 2023·17m
  24. 24

    Automated Interpretation of Clinical Electroencephalograms Using Artificial Intelligence

    Jun 20, 2023·14m
  25. 25

    Risk of Parkinson Disease Among Camp Lejeune Veterans

    May 15, 2023·21m
  26. 26

    Prenatal Exposure to Antiseizure Medication and Psychiatric Disorders

    Apr 17, 2023·17m
  27. 27

    Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors

    Mar 27, 2023·20m
  28. 28

    Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke

    Feb 23, 2023·17m
  29. 29

    Endovascular Thrombectomy vs Medical Management Beyond 24 Hours of Last Known Well

    Dec 27, 2022·17m
  30. 30

    Autoimmune Encephalitis Misdiagnosis in Adults

    Nov 28, 2022·18m
  31. 31

    Evaluation of Simvastatin as a Disease-Modifying Treatment for Patients With Parkinson Disease

    Oct 31, 2022·19m
  32. 32

    Cancer Risk in Children of Mothers With Epilepsy and High-Dose Folic Acid Use During Pregnancy

    Sep 26, 2022·17m
  33. 33

    Association of Neurocritical Care With Outcomes for Adults With Brain Injury

    An interview with Dr.

    Aug 29, 2022·20m
  34. 34

    Efficacy of Benzodiazepines or Antihistamines for Patients With Acute Vertigo

    Jul 18, 2022·18m
  35. 35

    A Conversation With Dr Kirsten Bibbins-Domingo, JAMA's New Editor in Chief

    Hidden gem

    Kirsten Bibbins-Domingo discusses becoming editor-in-chief of JAMA and its affiliated journals after work as a physician, epidemiologist, UCSF professor, and U.S.

    Jul 5, 2022·22m·1 clip
  36. 36

    Structural Inequities for Historically Underserved Communities in the Adoption of Stroke Certification in the US

    Jun 27, 2022·24m
  37. 37

    Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability

    May 31, 2022·19m
  38. 38

    Postmortem Assessment of Olfactory Tissue Degeneration and Microvasculopathy in Patients With COVID-19

    Apr 11, 2022·17m
  39. 39

    Early Posttraumatic Seizures and Moderate to Severe Traumatic Brain Injury

    Feb 21, 2022·18m
  40. 40

    Infarct on Brain Imaging, Subsequent Ischemic Stroke, and Clopidogrel-Aspirin Efficacy

    Jan 18, 2022·17m
  41. 41

    Assessment of Erenumab Safety and Efficacy in Migraine With and Without Aura

    Interview with lead author discussing a study on erenumab's safety and efficacy for migraine with and without aura.

    Dec 20, 2021·20m
  42. 42

    Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Probable Dementia With Lewy Bodies

    Nov 22, 2021·19m
  43. 43

    Association of Increased Seizures During Rewarming With Abnormal Neurodevelopmental Outcomes at 2-Year Follow-up

    Interview with Dr.

    Oct 18, 2021·25m
  44. 44

    Use and Safety of Immunotherapeutic Management of N-Methyl-D-Aspartate Receptor Antibody Encephalitis

    Sep 20, 2021·24m
  45. 45

    Risk of Rupture After Intracranial Aneurysm Growth

    Aug 30, 2021·24m
  46. 46

    Seizure Prophylaxis After Spontaneous Intracerebral Hemorrhage

    Jul 26, 2021·22m