JAMA Cardiology Author Interviews

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Cardiology papers, questioned at clinical depth.

The gist

JAMA Cardiology Author Interviews is a clinical research companion for cardiovascular medicine. Episodes move from manuscript question to study design, findings, limitations, and practice implications with authors and JAMA editors at the table.

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About JAMA Cardiology Author Interviews

JAMA Cardiology Author Interviews treats cardiovascular research as a conversation that has to survive careful questioning. The format is simple. A JAMA Cardiology editor introduces a recently published manuscript, brings in the author or an accompanying editorial voice, and works through the study's premise, design, results, limits, and practical meaning. It is not a newsy recap. It is closer to a guided reading of the paper, with enough clinical context to show why the question matters and enough methodological detail to keep the discussion anchored. Recent episodes range widely across cardiology. Heart failure with preserved ejection fraction appears through both TTR amyloid research in older Black and Hispanic individuals and longer-term follow-up from personalized accelerated physiologic pacing. Atrial fibrillation returns in several forms, from remote monitoring and European Society for Cardiology research summaries to genetic testing questions around cardiomyopathy-associated variants. Prevention is a steady thread. Episodes consider CT coronary angiography as a way to influence lipid-lowering therapy, pharmacist referrals for evidence-based statin initiation, and population-level sodium reduction in South Africa. The show also spends real time on who gets studied. Its discussion of clinical trial representativeness focuses on recruitment, language barriers, health literacy, community trust, site support, digital outreach, travel costs, and the funding needed to include populations that have often been missed. The register is polished and academic. Still, the strongest exchanges are practical: what counts as a meaningful endpoint, how much confidence longer follow-up adds, why a subgroup result matters, and where clinicians should avoid underdiagnosis or undertreatment. Listeners hear editors and researchers challenge one another respectfully, often with an eye toward implementation rather than novelty alone. The result is a compact, journal-linked series for people who want cardiology evidence explained with rigor, context, and restraint.

Made for: This show is for cardiologists, cardiovascular researchers, trainees, and evidence-focused clinicians who want direct context around JAMA Cardiology studies. It also suits medical listeners who prefer measured editorial discussion over simplified health advice.

What sets it apart: The show stands out by pairing article authors with JAMA Cardiology editors who press on design choices, endpoints, representativeness, and clinical translation. It stays close to the published evidence while still explaining why the findings matter in practice.

In their own words

Interviews with authors of articles from JAMA Cardiology. JAMA Cardiology publishes exceptional original research, state-of-the-art reviews, and informative opinions that advance the science and practice of cardiology, enhance cardiovascular health, and inform health care policy. JAMA Cardiology is the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine worldwide.JAMA Cardiology focuses on all aspects of cardiovascular medicine, including epidemiology and prevention, diagnostic testing, interventional and pharmacologic therapeutics, translational research, health care policy and outcomes, and global health.

As heard by us

Based on 5 episodes we listened to · August 2026

Study authors walk trial design, statistical limits, and enrollment gaps through with JAMA Cardiology's hosts, one paper at a time.

JAMA Cardiology Author Interviews sticks to one well-defined space: cardiovascular research published in the journal, discussed by the people who actually ran the studies.

Read our full review in PlayNext →

Why you'd press play

You get the trial readout, then the part where the caveats put on a tie.

Press play if you want

  • the cardiology paper walk-through before your confidence outruns the confidence interval
  • authors pressed on endpoints, sample size, follow-up, and what the data cannot quite prove
Read the full recommendation in PlayNext →
heart failure with preserved ejection fractionatrial fibrillationcardiac amyloidosispreventive cardiologyclinical trial representativenessstatin initiationsodium reduction policycardiovascular genetics

Talks about

Best episodes of JAMA Cardiology Author Interviews

Short reviews from the PlayNext desk, based on the episodes we processed.

From the JAMA Network: From ESC: Remote Monitoring for Atrial Fibrillation, Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction, and moreSep 16, 2025

A cardiology congress roundup finds its value in weighing promising results against the limits of the evidence.

Cardiology evidence gets a practical stress test in this special JAMA Editor's Summary on research presented at the European Society for Cardiology Congress.

Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals With Heart FailureSep 10, 2025

A focused look at how deliberate enrollment can reshape thinking about cardiac amyloidosis diagnosis.

The SCAN-MP study gives this episode its focus: how transthyretin cardiac amyloidosis shows up in older Black and Hispanic people with heart failure, and what more intentional enrollment can uncover about diagnosis.

Clinical Outcomes With Personalized Accelerated Physiologic Pacing in HFpEFAug 27, 2025

Longer-term MyPACE follow-up asks whether a higher resting heart rate belongs in the HFpEF pacing conversation.

HFpEF often makes the slower-heart-rate argument sound logical: more time should mean better filling. This PlayNext review finds the MyPACE discussion useful because it pushes against that instinct with longer-term follow-up in patients paced to raise resting heart rate. Dr.

Preserving and Promoting Clinical Trial RepresentativenessJul 30, 2025

A grounded discussion of how clinical trials can better reflect the people they are meant to serve.

Clinical trial representativeness is treated here as a practical design challenge, not an abstract ideal. Bob Bono and Dr. Roxana Moran keep the focus on what it takes to reach patients who have historically been difficult to enroll: community engagement, attention to social…

CT Angiography, Healthy Lifestyle Behaviors, and Preventive TherapyJun 18, 2025

A concise look at how CT angiography may make preventive therapy feel more actionable.

A CT scan can make preventive cardiology feel less like a risk estimate and more like something a patient can see. This JAMA Cardiology conversation keeps its focus on that practical turn, as Anne-Marie Navar asks Dr. Michael McDermott and Dr.

Podcasts like JAMA Cardiology Author Interviews

Episodes

  1. 1

    From the JAMA Network: From ESC: Remote Monitoring for Atrial Fibrillation, Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction, and more

    Hidden gem

    JAMA editors discuss cardiology research presented at the European Society for Cardiology Congress, including trials on atrial fibrillation screening.

    Sep 16, 2025·38m·2 clips
  2. 2

    Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Individuals With Heart Failure

    Hidden gem

    Among 650 participants, cardiac amyloidosis was about 6.5% to 7% overall and 17% in men over 75.

    Sep 10, 2025·18m·1 clip
  3. 3

    Clinical Outcomes With Personalized Accelerated Physiologic Pacing in HFpEF

    Hidden gem

    Three people switched from usual care to "my pace," and all three felt better and stayed there.

    Aug 27, 2025·21m·1 clip
  4. 4

    Preserving and Promoting Clinical Trial Representativeness

    Hidden gem

    Dr. Roxana Moran says trial inclusiveness must start with inclusion and exclusion criteria, patient recruitment, and retention.

    Jul 30, 2025·16m·1 clip
  5. 5

    CT Angiography, Healthy Lifestyle Behaviors, and Preventive Therapy

    Hidden gem

    Anne-Marie Navar speaks with Michael McDermott of the University of Edinburgh and Pam Douglas of Duke University about a nested SPOT-HART 2 study in JAMA Cardiology.

    Jun 18, 2025·19m·1 clip
  6. 6

    Cardiomyopathy-Associated Gene Variants in Atrial Fibrillation

    The study found cardiomyopathy-associated variants were twice as common among people with atrial fibrillation, rising to five times as common when AF began before age 45.

    Apr 30, 2025·15m·1 clip
  7. 7

    Encouraging Pharmacist Referrals for Evidence-Based Statin Initiation

    Dr.

    Mar 26, 2025·20m·1 clip
  8. 8

    Sodium Reduction Legislation and Urinary Sodium and Blood Pressure in South Africa

    JAMA Cardiology Author Interviews compares South Africa’s sodium legislation with China’s SAS salt-substitution trial.

    Feb 5, 2025·18m·1 clip
  9. 9

    Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation

    Nov 6, 2024·11m
  10. 10

    Heart Failure Medical Therapy Score and Clinical Outcomes

    Sep 25, 2024·15m
  11. 11

    Prevalence, Cardiac Phenotype, and Outcomes of Transthyretin Variants

    Aug 28, 2024·20m
  12. 12

    Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure

    Jul 31, 2024·20m
  13. 13

    Postpartum Ambulatory Blood Pressure and New-Onset Hypertensive Disorders of Pregnancy

    Jun 12, 2024·18m
  14. 14

    Osteosarcopenia and Mortality in Older Adults Undergoing Transcatheter Aortic Valve Replacement

    May 15, 2024·23m
  15. 15

    Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction

    Apr 17, 2024·19m
  16. 16

    A Revised Definition of Left Bundle Branch Block Using Time to Notch in Lead I

    Mar 27, 2024·17m
  17. 17

    Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV

    Feb 21, 2024·21m
  18. 18

    Effect of Tafamidis on Cardiac Function in Patients With Transthyretin Amyloid Cardiomyopathy

    Nov 15, 2023·22m
  19. 19

    Viability and Outcomes With Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction

    An interview with researchers discussing the viability sub-study of the REVIVED-BCIS2 trial on PCI for patients with severe coronary artery disease and left ventricular dysfunction.

    Oct 25, 2023·21m
  20. 20

    Prevalence and Overlap of Cardiac, Renal, and Metabolic Conditions in US Adults, 1999-2020

    Sep 27, 2023·18m
  21. 21

    Assisted Reproductive Technologies and Maternal Cardiovascular Disease

    Aug 9, 2023·12m
  22. 22

    Tracking Treatment Response in Cardiac Light-Chain Amyloidosis With Native T1 Mapping

    An interview with researchers discussing a study on tracking treatment response in cardiac AL amyloidosis using native T1 mapping.

    Jul 19, 2023·21m
  23. 23

    Percutaneous Microaxial Left Ventricular Assist Device for Patients With Cardiogenic Shock

    Jun 21, 2023·20m
  24. 24

    Vigorous Exercise in Patients With Hypertrophic Cardiomyopathy

    May 17, 2023·21m
  25. 25

    Ultrasound Renal Denervation in the Sham-Controlled RADIANCE II, RADIANCE-HTN SOLO, and RADIANCE-HTN TRIO Trials

    Apr 26, 2023·17m
  26. 26

    Association of Preexisting Heart Failure With Outcomes in Older Patients With Diffuse Large B-Cell Lymphoma

    Mar 29, 2023·21m
  27. 27

    Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care

    Feb 15, 2023·27m
  28. 28

    Structural Valve Deterioration After Self-Expanding Transcatheter or Surgical Aortic Valve Implantation

    Dec 14, 2022·17m
  29. 29

    Effect of Nudges to Clinicians, Patients, or Both to Increase Statin Prescribing

    Nov 30, 2022·17m
  30. 30

    Treatment of Hypertension in 2022

    Nov 8, 2022·27m
  31. 31

    Longer-Term All-Cause and Cardiovascular Mortality With Intensive Blood Pressure Control

    Oct 12, 2022·17m
  32. 32

    Burden of Rare Genetic Variants in Spontaneous Coronary Artery Dissection With High-risk Features

    Sep 14, 2022·20m
  33. 33

    Alerting Clinicians to 1-Year Mortality Risk in Patients Hospitalized With Heart Failure

    Aug 10, 2022·17m
  34. 34

    Association of LV Remodeling Assessment by CMR With Outcomes in Patients With Chronic Aortic Regurgitation

    Jul 20, 2022·20m
  35. 35

    Machine Learning–Based Models Incorporating SDOH vs Traditional Models for Predicting In-Hospital Mortality For Heart Failure

    Jul 6, 2022·14m
  36. 36

    A Conversation With Dr Kirsten Bibbins-Domingo, JAMA's New Editor in Chief

    An interview with the new editor-in-chief of JAMA discussing her career trajectory and interest in cardiovascular disease prevention.

    Jul 5, 2022·22m
  37. 37

    Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes

    May 11, 2022·25m
  38. 38

    Sex and Race Differences in NT-proBNP Concentration and Absolute Risk of Heart Failure in the Community

    Apr 27, 2022·12m
  39. 39

    Performance of Guideline-Recommended Strategies for Hospitalized Patients With STEMI in China

    Mar 16, 2022·14m
  40. 40

    N-Terminal Pro-Brain Natriuretic Peptide Measurements in Patients With Aortic Stenosis

    Feb 16, 2022·21m
  41. 41

    Association of Plaque Location and Vessel Geometry With Future ACS–Causing Culprit Lesions

    Jan 26, 2022·21m
  42. 42

    Association of Health Care Processes With Racial or Ethnic Disparities in Blood Pressure Control

    Dec 8, 2021·23m
  43. 43

    Treatment With Sacubitril/Valsartan in Patients With Advanced Heart Failure and Reduced Ejection Fraction

    Nov 3, 2021·17m
  44. 44

    Long-term Clinical Outcomes of Skeletonized vs Pedicled Internal Thoracic Artery Harvesting in the ART Trial

    Sep 29, 2021·28m
  45. 45

    Association of Myocardial Blood Flow Reserve With Adverse Left Ventricular Remodeling in Patients With Aortic Stenosis

    Sep 15, 2021·17m
  46. 46

    Transthyretin Amyloid Cardiomyopathy in Patients With Heart Failure With Preserved Ejection Fraction

    Aug 25, 2021·21m
  47. 47

    Posttraumatic Stress Disorder and Cardiovascular Disease

    Jul 14, 2021·21m
  48. 48

    Prevalence of Coronary Artery Disease and Coronary Microvascular Dysfunction in Heart Failure

    Jun 23, 2021·22m
  49. 49

    Association of Socioeconomic Disadvantage With Long-term Mortality After Myocardial Infarction

    May 19, 2021·17m