Genetics Unzipped

The Genetics Society

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In their own words

From Mendel's peas to personal genome sequencing, Genetics Unzipped brings you stories from the world of genes, genomes and DNA. In association with The Genetics Society.

As heard by us

Based on 5 episodes we listened to · September 2026

Expert interviews connect genetic mechanisms to medicine, evolution and animal behavior while keeping uncertainty visible.

Genetics Unzipped follows genes from molecular machinery into medicine and animal behavior, with Sally LePage and Kat Arney guiding expert interviews through precise, approachable questions.

Read our full review in PlayNext →

Why you'd press play

Between glowing squid in space and genetically modified pig hearts, your curiosity has options.

Press play if you want

  • to hear Kat Arney press on what a cancer blood test could miss in a small tube
  • to let Sally LePage turn black widow mating into a question about reproductive advantage
Read the full recommendation in PlayNext →

Talks about

Best episodes of Genetics Unzipped

Short reviews from the PlayNext desk, based on the episodes we processed.

In the bloodJun 23, 2022

A clear look at what cancer DNA in blood can reveal, and what one tube can miss.

Blood sits at the centre of this episode as both a revealing signal and a limited sample. Kat Arney's conversation with Susan Galbraith, Executive Vice President for Oncology R&D at AstraZeneca, follows circulating tumour DNA through the appeal of liquid biopsies: detecting…

When should you eat your relatives?Jun 2, 2022

A macabre look at cannibalism as survival tactic, reproductive strategy, and sibling rivalry.

Cannibalism lands as a grim calculation in this darkly playful Genetics Unzipped episode, where the danger of killing for food gives way to stranger advantages in the natural world.

Squid GameMay 19, 2022

A bright, accessible tour of squid genetics, bacterial partnerships, ingenious eggshells, and baby squid in space.

Genetics Unzipped uses Squid Game as a springboard into real squid science, moving from cephalopod basics to the genetic puzzles that make these animals so hard to study.

Nature, Nurture and 'The Wobble'May 5, 2022

A clear cellular-scale look at how random shifts in gene activity can matter when a biological system is already disrupted.

Genetics Unzipped revisits the familiar nature-and-nurture debate at the scale of a developing cell, then makes room for a third influence: chance.

Have a heartApr 21, 2022

A clear, measured look at the genetic engineering and open questions behind a pig-to-human heart transplant.

Genetics Unzipped brings xenotransplantation down from science fiction and into the hospital ward, tracing the first transplant of a genetically modified pig heart into a human.

Podcasts like Genetics Unzipped

Episodes

  1. 1

    The battle for biology

    This episode explores the historical impact of Gregor Mendel and William Bateson on genetics, questioning if a Weldonian perspective could have offered an alternative view.

    ·43m
  2. 2

    Dumb luck

    Dr.

    ·29m
  3. 3

    Kings, car parks and consent

    This episode explores the ethical considerations of extracting and sequencing DNA from ancient human remains, featuring an interview with Professor Thierry King about his work identifying King Richard III's remains.

    ·28m
  4. 4

    BONUS Re-release

    This bonus episode of Genetics Unzipped re-releases an interview with Dr.

    ·29m
  5. 5

    GMO or GM NO?

    This episode explores the history, current applications, and ethical considerations of genome editing technologies, from basic research to human genetic disease treatment.

    ·37m
  6. 6

    Living with the Eugenic Past: Michele Goodwin

    This episode features an interview with Michele Goodwin discussing how the legacy of eugenics and white supremacy persists in modern society and institutions.

    ·18m
  7. 7

    Living with the Eugenic Past: Elaine Riddick

    This episode features an interview with Elaine Riddick, a survivor of forced sterilization under eugenic policies, discussing her personal story and broader questions about justice, institutional responsibility, and learning from the eugenic past.

    ·17m
  8. 8

    Space invaders

    This episode explores how tardigrades, microscopic animals that survive extreme conditions like boiling, freezing, and space exposure, can teach us about desiccation, vaccine delivery, and space travel through an interview with molecular biologist Professor Thomas Boothby.

    ·29m
  9. 9

    Hap-pea 200th birthday, Mendel!

    This episode celebrates the 200th anniversary of Gregor Mendel's birth by exploring his life, work, and the modern genetics research that builds on his foundational discoveries.

    ·36m
  10. 10

    Living with the Eugenic Past: Brian Donovan

    This interview with Dr.

    ·15m
  11. 11

    That's so extra

    This episode explores extra-chromosomal DNA, its functions and genetic implications, while also promoting a related BBC Radio 4 documentary series on cancer's history, treatment challenges, and future research.

    ·33m
  12. 12

    Living with the Eugenic Past: Adam Rutherford

    This episode features an interview with Dr.

    ·17m
  13. 13

    Bye-bye boys

    This episode explores whether new gene technologies and climate change could lead to the extinction of males, focusing on genetic sex determination across various species.

    ·36m
  14. 14

    Tracking COVID and tackling obesity

    This episode features interviews with Genetics Society award winners Cecilia Lindgren on obesity genetics and Lucy Van Dorp on COVID-19 spread tracking, recorded at a symposium celebrating DNA's 70th anniversary.

    ·33m
  15. 15

    Next Generation Sequence

    This episode of Genetics Unzipped discusses the future of the podcast, including a listener survey for funding decisions and a focus on rising stars in genetics, potentially as a final episode.

    ·38m
  16. 16

    Confident, competent or confused

    This episode explores a survey on public knowledge and attitudes toward genetics, discussing how the COVID-19 pandemic influenced science engagement and perceptions.

    ·39m
  17. 17

    Da Vinci’s DNA

    This episode explores how DNA technology is being used to detect art forgery and uncover genetic secrets from historical figures like Da Vinci, Van Gogh, and Beethoven.

    ·26m
  18. 18

    40 years of HIV

    This episode explores the 40-year history of HIV/AIDS, tracing its discovery and impact from early cases in 1981 to modern understanding.

    ·35m
  19. 19

    Big Biology Bonus

    This bonus episode of Genetics Unzipped introduces and features the podcast Big Biology, including an interview with its hosts about their show's focus on conversations with active scientists covering diverse biological topics like rice domestication.

    ·1h 15m
  20. 20

    Chris Hemsworth took a genetic test for Alzheimer's.

    This episode explores Chris Hemsworth's genetic test revealing high Alzheimer's risk, discussing the ApoE gene, direct-to-consumer genetic testing like 23andMe, and insights from a genetic counselor.

    ·38m
  21. 21

    S525: 2022 Unzipped

    This episode of Genetics Unzipped reviews the top genetic stories of 2022, including a pig heart transplant, Nobel Prize winner Svante Perbo's work on extinct human genomes, and Gregor Mendel's bicentennial.

    ·40m
  22. 22

    Food for the future

    This episode explores how plants adapt to environmental changes and how genetic research can help ensure sustainable food production for the future.

    ·44m
  23. 23

    Let there be light

    This episode explores the origins of photosynthesis and the chloroplast genome, focusing on eukaryotic organisms and the role of the nucleus in genetic control.

    ·26m
  24. 24

    Pop goes the genome!

    This episode explores how genetics appears in popular culture, from movies and music to baking, featuring an interview with scientist and baker Shabira Yousaf.

    ·34m
  25. 25

    Living with the Eugenic Past: Joe Cain

    This episode explores the historical legacy of eugenics through an interview with Professor Joe Cain, focusing on how institutions like University College London have grappled with their connections to Francis Galton and the eugenics movement.

    ·16m
  26. 26

    The Genesis Machine

    This episode explores the current and future possibilities of genetic engineering and synthetic biology, discussing both the transformative benefits and potential risks of technologies like CRISPR and DNA synthesis.

    ·38m
  27. 27

    Living with the Eugenic Past: Anneke Lucassen

    This episode features an interview with Professor Anneke Lucassen discussing the challenges of addressing eugenics' legacy, diversity in genomic databases, and ethical issues in genomic medicine.

    ·14m
  28. 28

    2023 Unzipped

    This episode is a compilation of unaired clips from favorite interviews in 2023, while also requesting listener feedback on the podcast's future funding and direction.

    ·36m
  29. 29

    Double helix double crossing

    This episode explores the nuanced historical reality behind the discovery of DNA's double helix structure, challenging the simplified narrative of Watson and Crick stealing credit from Rosalind Franklin.

    ·52m
  30. 30

    S609: Raiders of Noah’s Ark

    This episode explores how researchers are studying animal genomes to find genetic adaptations that could lead to breakthroughs in human health, particularly in cancer therapy.

    ·27m
  31. 31

    Making Big Science Happen

    This episode explores the behind-the-scenes work at a leading genomics institute, featuring an interview with Cordelia Langford about her career and the evolution of genetic research from early DNA sequencing to the Human Genome Project.

    ·26m
  32. 32

    An Evolutionary Revolutionary

    This episode explores the story of Alfred Russell Wallace, the co-discoverer of natural selection who is often overshadowed by Charles Darwin, through an interview with evolutionary biologist Professor Jim Costa.

    ·32m
  33. 33

    S6.02: Would you Adam and Eve it?

    This episode explores the genetic origins of humanity by examining the concepts of genetic Adam and Eve, their historical context, and how we should refer to these ancient ancestors.

    ·30m
  34. 34

    Living with the Eugenic Past: Turi King

    This episode explores the history and recent name change of the Adelphi Genetics Forum, formerly known as the Eugenics Education Society and Galton Institute, as it grapples with its eugenic past and aims to promote responsible genetics research.

    ·11m
  35. 35

    Bats, boats and buried bodies

    This episode explores the field of environmental DNA (eDNA), discussing how it can detect animals and human remains through environmental samples like air and mud, with insights from Professor Elizabeth Clare.

    ·39m
  36. 36

    Little Shop of Genetic Horrors

    This episode explores the biology and evolution of carnivorous plants, focusing on pitcher plants and their insect-trapping mechanisms, featuring an interview with researcher Ulrike Bauer.

    ·40m
  37. 37

    Meet the DNA Detectives hunting the causes of cancer

    This episode follows DNA detectives from the Mutagraphs of Cancer project in Kenya as they investigate the genetic causes of cancer by analyzing genomic fingerprints.

    ·33m
  38. 38

    The diagnosis odyssey

    This episode explores the challenging journey patients with rare genetic disorders face in getting diagnoses, the research into how gene variations cause disease, and new treatment approaches.

    ·38m
  39. 39

    Birds and bees… and sardines

    This episode explores how genetics influences animal behaviors such as migration in birds, bees, and sardines, examining whether these patterns are hardwired in their DNA.

    ·25m
  40. 40

    Genes, junk and the ‘dark genome’

    This episode explores the latest release of half a million whole genome sequences from UK Biobank and examines how this data will advance medical research by investigating the dark genome and questioning how much of human DNA is actually junk.

    ·38m
  41. 41

    Bread and fishes

    This episode explores how geneticists are addressing food security challenges posed by climate change, focusing on wheat shortages caused by factors like war, heatwaves, droughts, and floods.

    ·36m
  42. 42

    S5.17 Genetics of Society

    This episode explores the genetics of social hierarchies in honeybee societies, examining why rigid structures exist where workers serve queens and reproductive rights are controlled.

    ·26m
  43. 43

    Vax to the future

    This episode explores the science, history, and future potential of DNA and RNA vaccines, tracing their development from early smallpox vaccination to modern applications.

    ·33m
  44. 44

    BONUS - Hormones: The Inside Story - Season 3

    This bonus episode introduces the podcast 'Hormones: The Inside Story' and previews an episode exploring the genetics, ethnicity, and maternal factors influencing type 2 diabetes.

    ·40m
  45. 45

    Baby brain, baby body

    This episode explores the genetic links between birth weight and diabetes risk, and the role of prolactin in pregnancy, while also promoting a science communication workshop for genetics PhD students.

    ·31m
  46. 46

    Past to present

    This episode explores how ancient DNA analysis reveals insights into human evolution, featuring Nobel Prize-winning geneticist Svante Pebo's work on Neanderthal genomes.

    ·23m
  47. 47

    Does size matter when it comes to your genes?

    This episode explores whether genome size matters, starting with the 2001 draft human genome sequence.

    ·25m·2 clips
  48. 48

    Genes, brains and the mind

    This episode explores the role of genetics in shaping personality, featuring an interview with Kevin Mitchell, who discusses brain development, behavioral genetics, and the interplay between genes and environment.

    ·34m·3 clips
  49. 49

    Genetics at your fingertips

    This episode explores the genetics of fingerprints, covering topics from genetic fingerprinting in crime to the unique patterns in primates and koalas, with a humorous story about chimps at London Zoo.

    ·29m·2 clips
  50. 50

    Time of your life

    Nov 2, 2023
  51. 51

    In the blood

    Hidden gem

    Genetics Unzipped's "In the blood" examines ctDNA, the tumour DNA fragments that can be detected in a blood draw and used to track cancer development, progression, and treatment response.

    Jun 23, 2022·30m·3 clips
  52. 52

    *Repost* Strands of life

    Jun 16, 2022
  53. 53

    When should you eat your relatives?

    Hidden gem

    Dr Sally LePage opens Genetics Unzipped by asking when animals should eat relatives, then ties the question to Foray ritual cannibalism and Kuru in Papua New Guinea.

    Jun 2, 2022·36m·2 clips
  54. 54

    Squid Game

    Hidden gem

    Genetics Unzipped uses Squid Game as a hook while Dr Sally LePage connects squid genetics, egg biology, and bacterial symbiosis.

    May 19, 2022·34m·2 clips
  55. 55

    Nature, Nurture and 'The Wobble'

    Hidden gem

    Ben Lehner's worms showed the same mutation could hit 80% of animals, or only 50%.

    May 5, 2022·21m·1 clip
  56. 56

    Have a heart

    Hidden gem

    Genetics Unzipped with Dr Sally LePage examines xenotransplantation through the first genetically modified pig heart transplanted into 57-year-old David Bennett in January.

    Apr 21, 2022·28m·1 clip
  57. 57

    Face to face

    Apr 7, 2022·26m
  58. 58

    Introducing Exosomes

    Mar 24, 2022·34m
  59. 59

    Sex and the Single Cell

    Mar 10, 2022·28m
  60. 60

    Genetics of the Americas

    Feb 24, 2022·37m
  61. 61

    On Growth and Form

    Feb 10, 2022·28m
  62. 62

    Breeding better humans

    Jan 27, 2022·35m
  63. 63

    How the zebra got its stripes

    Jan 13, 2022·40m
  64. 64

    *Repost* Sex and death

    Jan 6, 2022·30m
  65. 65

    Best of 2021

    Dec 16, 2021·34m
  66. 66

    The Natural Lottery

    Dec 2, 2021·29m
  67. 67

    A menagerie of malignancy

    Nov 18, 2021·23m
  68. 68

    Bonus: Hormones: The Inside Story - Season 2

    Nov 11, 2021·22m
  69. 69

    Wired for sound

    Nov 4, 2021·40m
  70. 70

    Rarities and Oddities

    Oct 21, 2021·22m
  71. 71

    Baby boom

    Oct 7, 2021·39m
  72. 72

    Reading the book of life

    Sep 23, 2021·26m
  73. 73

    Meet the Robinson Crusoe Islanders

    Sep 9, 2021·35m
  74. 74

    Back to the beginning

    Aug 26, 2021·24m
  75. 75

    Direwolves and Denisovans

    Aug 12, 2021·40m
  76. 76

    Catching cancer

    Jul 29, 2021·34m
  77. 77

    Genes for all

    Jul 15, 2021·35m
  78. 78

    Six toed cats and cyclops lambs

    Jul 1, 2021·31m
  79. 79

    Why me?

    Jun 17, 2021·37m
  80. 80

    From genes to drugs to bugs

    Jun 3, 2021·41m
  81. 81

    Creatures of the night

    May 20, 2021·32m
  82. 82

    Genes and giants

    May 6, 2021·36m
  83. 83

    Making better medicines

    Apr 22, 2021·40m
  84. 84

    A brief history of CRISPR

    Apr 8, 2021·36m
  85. 85

    Suffrage Science: Dr Tamsin Edwards

    Apr 1, 2021·34m
  86. 86

    Giving nature a helping hand

    Mar 25, 2021·48m
  87. 87

    How to be a superhero

    Mar 11, 2021·30m
  88. 88

    Dogology

    Feb 25, 2021·44m
  89. 89

    A dominant character

    Feb 11, 2021·34m
  90. 90

    100 not out?

    Jan 28, 2021·36m
  91. 91

    Genes and vaccines

    Jan 14, 2021·32m
  92. 92

    Genes and Vaccines

    Jan 14, 2021·37m
  93. 93

    Repost: Chimps, cancer genes and missing kids

    Jan 7, 2021·33m
  94. 94

    Not just the wife

    Dec 31, 2020·32m
  95. 95

    Genetics Shambles 12

    Dec 24, 2020·40m
  96. 96

    Repost: When 'Becky' met Bateson

    Dec 17, 2020·33m
  97. 97

    Repost: Uprooting the tree of life

    Dec 10, 2020·30m
  98. 98

    Are my hormones making me fat?

    Dec 3, 2020·29m
  99. 99

    Genetics Shambles 11: Prof Steve Jones

    Nov 26, 2020·43m
  100. 100

    Best bits of Genetics Unzipped 2020

    Nov 19, 2020·32m
  101. 101

    Genetics Shambles 10: In conversation with Prof Aoife McLysaght

    Nov 12, 2020·50m
  102. 102

    Heat, Stick, Duplicate, Repeat

    Nov 5, 2020·30m
  103. 103

    Genetics Shambles 9: The ethics of genetics

    Oct 29, 2020·53m
  104. 104

    Past Present and Future of the Human Genome Project

    Oct 22, 2020·31m
  105. 105

    Genetics Shambles 8: New genetic technologies

    Oct 15, 2020·51m
  106. 106

    From Philadelphia to Baltimore

    Oct 8, 2020·33m
  107. 107

    Genetics Shambles 7: COVID expert panel 3

    Oct 1, 2020·1h 16m
  108. 108

    The Future of Cancer

    Sep 24, 2020·45m
  109. 109

    Genetics Shambles 6: Dealing with pathogens

    Sep 17, 2020·55m
  110. 110

    Making Babies and Getting Organised

    Sep 10, 2020·27m
  111. 111

    Genetics Shambles 5: The evolution of cancer

    Sep 3, 2020·59m
  112. 112

    Rare, Well Done

    Aug 27, 2020·35m
  113. 113

    Genetics Shambles 4: The sequence of everything

    Aug 20, 2020·55m
  114. 114

    Rebel Cell

    Aug 13, 2020·38m
  115. 115

    GS 03 Humans: evolved and evolving

    Aug 6, 2020·54m
  116. 116

    Sickness and susceptibility

    Jul 30, 2020·35m
  117. 117

    GS 02 A guide to the human genome

    Jul 23, 2020
  118. 118

    Pimp My Genome

    Jul 16, 2020·32m
  119. 119

    GS 01 COVID-19 and Learning from the Past

    Jul 9, 2020·51m
  120. 120

    The eyes have it

    Jul 2, 2020·37m
  121. 121

    The Cancer Ladies

    Jun 18, 2020·33m
  122. 122

    Out Standing in the Field

    Jun 4, 2020·33m
  123. 123

    From one generation to the next

    May 21, 2020·31m
  124. 124

    Out of Africa

    May 7, 2020·36m
  125. 125

    Twisted history

    Apr 23, 2020·21m
  126. 126

    Nothing About Me Without Me

    Apr 9, 2020·33m
  127. 127

    An Accidental Invention

    Mar 26, 2020·28m
  128. 128

    Can you have a 'perfect genome'?

    Mar 12, 2020·30m
  129. 129

    Poop, pus and the Manhattan project

    Feb 27, 2020·24m
  130. 130

    Race to the Bottom

    Feb 13, 2020·29m
  131. 131

    Fish, facts and fiction - from Haeckel’s embryos to Tiktaalik

    Jan 30, 2020·21m
  132. 132

    Hidden family secrets revealed by genetic testing

    Jan 16, 2020·35m
  133. 133

    Investigating the icons of evolution

    Jan 2, 2020·23m
  134. 134

    Ancient DNA and the changing structure of the prehistoric British population

    Dec 19, 2019·13m
  135. 135

    Genetics and history: how DNA can be used as a window onto the past

    Dec 19, 2019·10m
  136. 136

    The 'Celts' in Britain - a romantic fiction?

    Dec 19, 2019·10m
  137. 137

    The genomic history of Ireland

    Dec 19, 2019·9m
  138. 138

    The genetic structure of the populations of the British Isles -

    Dec 19, 2019·10m
  139. 139

    03 - The First Britons: bones and behaviour

    Dec 19, 2019·9m
  140. 140

    Investigating the earliest humans in Europe

    Dec 19, 2019·7m
  141. 141

    Sperm wars, sneaky sheep and substandard stallions

    Dec 5, 2019·35m
  142. 142

    Uprooting the Tree of Life

    Nov 21, 2019·30m
  143. 143

    The future is now

    Nov 7, 2019·40m
  144. 144

    When 'Becky' met Bateson

    Oct 24, 2019·33m
  145. 145

    Exploring the Poop-ome, from the Microbiome to Metagenomics

    Oct 10, 2019·34m
  146. 146

    Mergers and Acquisitions

    Sep 26, 2019·35m
  147. 147

    Big Questions about the Big C

    Sep 12, 2019·29m
  148. 148

    In case you missed it...

    Aug 29, 2019·33m
  149. 149

    Sex and Death

    Aug 15, 2019·30m
  150. 150

    The Genetic Time Machine

    Aug 1, 2019·34m
  151. 151

    Cut. Paste. Pair. Repeat.

    Jul 18, 2019·25m
  152. 152

    Happy 100th birthday to us!

    Jul 4, 2019·27m
  153. 153

    Genetics by Numbers

    Jun 20, 2019·26m
  154. 154

    Up The Garden Path

    Jun 6, 2019·22m
  155. 155

    The Seeds of a Great Idea

    May 23, 2019·19m
  156. 156

    The Zero Dollar Genome

    May 9, 2019·34m
  157. 157

    Strands of life

    Apr 25, 2019·28m
  158. 158

    Darwin vs Mendel

    Apr 11, 2019·31m
  159. 159

    Not 'just the wife'

    Mar 28, 2019·31m
  160. 160

    Chimps, cancer genes and missing kids

    Mar 14, 2019·33m
  161. 161

    Getting ready for genomic medicine

    Mar 4, 2019·36m
  162. 162

    007 - Supermodels of Science

    Feb 28, 2019·20m
  163. 163

    006 - Big Fat Failure

    Feb 14, 2019·31m
  164. 164

    005 - Vegetable soup

    Jan 31, 2019·19m
  165. 165

    004 - Witness the fitness

    Jan 17, 2019·32m
  166. 166

    003 - Hunting Huntington's, Nobel viruses and spidergoats

    Jan 3, 2019·28m
  167. 167

    002 - Behind the scenes at the Christmas Lectures

    Dec 20, 2018·32m
  168. 168

    001 - Get unzipped!

    Dec 12, 2018·5m