Core IM Team
219 episodes listed below
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Core Internal Medicine via following series: 5 Pearls || Clinically relevant pearls Mind the Gap || Why do we do what we do? Gray Matters || Management Reasoning Hoofbeats || Dissecting clinical reasoning At the Bedside || Explore everyday challenges
Based on 6 episodes we listened to · September 2026
Clinical questions, careful distinctions, and decision-level detail make Core IM a practical guide to reasoning through complicated internal medicine cases.
Core IM | Internal Medicine Podcast turns clinical uncertainty into a sequence of answerable questions. Its conversations move from dementia assessment and treatment eligibility to procedural bleeding risk, neutropenia, invasive fungal disease, and cardiovascular risk.
The INR has an opinion; your proceduralist gets a vote.
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Short reviews from the PlayNext desk, based on the episodes we processed.
A clear take on congestion, Doppler limits, and bedside judgment.
This episode gives a grounded look at venous congestion and treats low urine output as a judgment problem, not a simple fluids puzzle. It stays most convincing when it explains what Doppler can and cannot show, and it keeps the combined score in perspective instead of pretending…
A practical constipation-medication refresher with mnemonics that stick.
The piece walks through constipation treatment in a clear, usable way. It separates osmotic and stimulant laxatives, then gets into the details that actually matter in practice: onset, side effects, and how well people tolerate them.
Clear counseling for severe hypertriglyceridemia, with concrete lifestyle steps patients can use right away.
Severe hypertriglyceridemia is treated as a serious issue, and the guidance stays firmly on the practical side. It keeps circling back to lifestyle changes, medications plus lifestyle interventions, and simple homework patients can act on right away: walking, no alcohol, no…
A practical diabetes debate that keeps clinical nuance tied to bedside reality.
This episode turns a diabetes decision into something concrete by following a patient with coronary artery disease, stage 3B CKD with albuminuria, and a normal BMI.
Privacy and confidentiality become practical when mandated reporting and bedside ethics meet.
Privacy and confidentiality are treated as everyday clinical work, not a box to tick. The discussion moves through domestic abuse, sexually transmitted infections, child abuse, elder abuse, and other mandated-reporting questions while keeping the patient at the center.
A focused look at why some neutropenias call for dose reduction while others demand an immediate stop.
This episode keeps its footing by drawing a clean line between dose-dependent neutropenia and the immune-mediated kind. That difference matters in practice: sometimes lowering the dose is enough, and sometimes the drug has to come off the table for good.
A clear, clinically useful look at a risk marker that is easy to overlook.
The segment treats Lp(a) as a risk marker worth knowing, and it keeps the discussion grounded. Shreya Trivedi and Ian Kelly move quickly through what the number means, why nmol/L is the cleaner unit, and why the real question is often how much risk it adds, not whether it lands…
A practical pneumothorax walkthrough that makes chest tube management easier to follow.
Pneumothorax gets treated like a bedside problem here, and that keeps the discussion grounded. The episode moves through diagnosis, initial management, who needs a chest tube, and the pleural drainage system without losing the thread.
Peter Attia evaluates longevity science, from CETP inhibitors to protein debates, through evidence.
Morning medical evidence, compressed for practice.
Medical research, translated through patient experience.
Dr.
Core IM | Internal Medicine Podcast #198 centers on Dr.
Core IM’s Dr.
At the Bedside turns to the places where privacy collides with duty.
This episode features an interview with Dr.
This episode of Core IM focuses on using storytelling in medicine to evoke emotional resonance and provide a break from overwhelming news cycles, featuring an interview with Dr.
Nick and Indu open by treating cognitive impairment as a hard conversation, not a neat diagnosis.
The conversation focuses on anti-amyloid treatment for early Alzheimer’s disease.
The episode breaks down neutropenia and febrile neutropenia through medication causes.
The episode opens with the familiar problem of low urine output and the tricky decision between fluids and diuretics.
The episode starts with a plain but important question: when diabetes treatment options stack up, where do you begin?
Nick and Shreya begin with a 72-year-old inpatient who comes in with syncope.
The episode starts with a simple problem: calling fungus rare can make people stop looking for it.
Severe hypertriglyceridemia is treated here as a real bedside problem, not just a lab value to file away.
Core IM's 5 Pearls segment on pneumothorax opens with the bedside problem of making sense of the chest tube black box.
Core IM and NEJM Group frame antibiotic duration around the BALANCE trial, a 3,600-plus patient study across seven countries that tested seven days versus 14 days for bacteremia.
Core-IM’s Neph Madness episode pairs Dr.
Core IM’s “Diagnose the Clinician: Hoofbeats Segment” follows a 72-year-old man with 2 weeks of abdominal pain, an 8-kilogram weight loss, leukocytosis to the 20s, bilirubin 4, and more than 20 liver masses with pancreatic, renal, and pelvic bone lesions.
Core IM’s Hypercoagulability Part 2 with Dr.
Core IM’s "Hepatorenal Syndrome Part 2 on Management" centers on raising MAP with vasoconstrictors, and the hosts say the treatment target is a 10 to 15 mmHg increase.
Nick and Trey return to an orthostatic hypotension case and spend time on the part that does not sit neatly inside a single label.
This episode explores Lp(a) as a genetically determined, independent risk factor for atherosclerotic cardiovascular disease, covering its mechanisms, testing guidelines, interpretation of levels, and management strategies including statins, aspirin, and PCSK9 inhibitors.
Core IM | Internal Medicine Podcast #175 focuses on the Purpose 1 and Purpose 2 trials of lenacapivir for HIV prevention, framed by Greg Katz, Clem Lee, and Abana Pearl.
Core IM | Internal Medicine Podcast #180 centers on REDUCE-AMI, the April 2024 NEJM randomized trial that enrolled about 5,000 post-MI patients across 45 centers in Sweden, Estonia, and New Zealand.
Core IM’s Beyond Journal Club with NEJM Group reviews insulin basics and the QUINT-1 trial of once-weekly insulin F-sitora in type 2 diabetes.
Core IM | Internal Medicine Podcast #189 centers on the NEJM Group collaboration Beyond Journal Club and the January 2025 Boland et al.
Core IM’s #178 segment on continuous glucose monitors focuses on how CGM data should change insulin decisions, not just how to read another number on a screen.
The hosts walk through three practical branch points for interventional radiology decision-making.
Pleural effusions are the focal point.
This episode discusses the CRAVE trial on coffee and arrhythmias, contextualizing landmark clinical research for internal medicine practitioners.
This episode of Core IM covers high-yield pearls on clotting and hypercoagulability, featuring expert insights and a quiz format.
This episode discusses the Apache study on microplastics, exploring how observational data can identify associations that may cause disease and the implications for everyday choices.
This episode explores the role of music therapy in hospice and palliative care through an interview with a music therapist.
Two physicians discuss a case of incidental lung findings in a child, exploring how to differentiate between benign conditions and early interstitial lung disease.
This episode covers five clinical pearls on monoclonal gammopathies, including presentation, initial workup, urine testing, and spectrum of disease.
This episode discusses the history of asthma pathophysiology and landmark trials, culminating in a deep dive into the Mandala trial on rescue drugs.
Two internists discuss the importance of CKD staging and how to apply it clinically.
This episode covers five clinical pearls on guideline-directed medical therapy for heart failure with reduced ejection fraction, including management in CKD, use of hydralazine/isosorbide dinitrate, ivabradine, inpatient vs outpatient initiation, and EF recovery.
This episode of Core IM's Hoofbeats series discusses diagnostic challenges and clinical reasoning, sponsored by Glass Health, a knowledge management tool for physicians.