ASCO Daily News

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Cancer research, translated for clinical judgment.

The gist

ASCO Daily News turns recent oncology research into structured conversations for clinical audiences. Episodes move from trial design and endpoints to treatment selection, toxicity, feasibility, and the questions that remain in practice.

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About ASCO Daily News

ASCO Daily News is a professional oncology briefing built around expert interviews and recent cancer research. Its center of gravity is clinical decision-making. Rather than flattening studies into headlines, episodes spend time on trial populations, endpoints, toxicity, access, feasibility, and the limits of evidence. The show assumes a medically fluent audience. Recent conversations have covered AI in oncology, high-risk smoldering multiple myeloma, EGFR-mutated non-small cell lung cancer, GU cancer data, head and neck cancer personalization, low-dose immunotherapy, GI cancer abstracts, and ASCO Annual Meeting research previews. The register is collegial and technical. Dr. Monty Powell often frames the conversation from the perspective of a medical oncologist, then brings in disease-focused guests to clarify what matters in the clinic. That structure gives the show a useful tension. New data are treated seriously, but not automatically as simple answers. An episode on AI emphasizes source checking, clinical context, hallucination risk, and the danger of letting convenience outrun judgment. The smoldering myeloma discussion considers daratumumab, fixed-duration treatment, early intervention, and the shift away from a pure watch-and-wait posture for selected high-risk patients. The EGFR-positive lung cancer episode weighs disease biology, patient priorities, and care-delivery feasibility. Symposium-highlight episodes function like curated conference notes, moving quickly through abstracts while still naming the clinical question behind each result. The head and neck cancer discussion follows circulating tumor DNA, HPV-related disease, surveillance, recurrence risk, and de-escalation studies. The low-dose pembrolizumab episode brings cost, toxicity, global access, and triple negative breast cancer into the same frame. The show is careful about boundaries. Its closing disclaimers repeatedly stress education and information rather than diagnosis or individual treatment. That matters because the material can be highly specific and consequential. ASCO Daily News is best for clinicians, researchers, trainees, and oncology-adjacent professionals who want to hear how specialists reason through changing evidence. It rewards listeners who already know the vocabulary. It also captures the texture of oncology as it is practiced now: biomarker-driven, trial-aware, cost-conscious, and full of judgment calls.

Made for: This show is for oncologists, oncology trainees, researchers, advanced practice clinicians, and medically fluent listeners following cancer trials and treatment standards. It suits people who want expert context, not simplified health advice.

What sets it apart: ASCO Daily News stands out by keeping the conversation close to clinical evidence and real-world decision points. Episodes connect conference data, trial design, biomarkers, toxicity, access, and patient priorities without turning research into hype.

In their own words

The ASCO Daily News Podcast features oncologists discussing the latest research and therapies in their areas of expertise.

Why you'd press play

An oncology trial sounds settled until Dr. Monty Powell asks what you'd actually change in practice.

Press play if you want

  • to weigh EGFR lung cancer treatments against toxicity and quality of life
  • to hear why watch-and-wait is being reconsidered for high-risk smoldering myeloma
Read the full recommendation in PlayNext →
oncology trial resultscancer treatment selectionAI in clinical practicebiomarkers and ctDNAtreatment toxicityASCO meeting highlightsglobal access to cancer carepractice-changing abstracts

Talks about

Best episodes of ASCO Daily News

Short reviews from the PlayNext desk, based on the episodes we processed.

'No Margin for Error': What to Know Before Implementing AI in Clinical PracticeApr 16, 2026

A grounded oncology review of AI's speed, source-checking, hallucination risk, and the clinical judgment that still has to lead.

AI in oncology is framed with the stakes kept in view: toxic treatments, clinical decisions, and cases where the margin for error can feel life and death. Dr.

Groundbreaking Results Shift Treatment Paradigm in High-Risk Smoldering Multiple MyelomaApr 2, 2026

A measured look at how AQUILA is pushing high-risk smoldering myeloma past watchful waiting.

High-risk smoldering multiple myeloma is making watch-and-wait feel less settled. Monty Powell leads Vincent Rajkumar, lead investigator of AQUILA and senior author on the manuscript, and Sadhu Somani through a focused discussion of daratumumab after its FDA approval in this…

Navigating Therapeutic Advances in EGFR-Mutated NSCLCMar 19, 2026

A grounded discussion of how clinicians weigh EGFR-positive lung cancer treatment choices against toxicity, logistics, and patient priorities.

Treatment choices in EGFR-positive lung cancer are presented here as a balance between efficacy, toxicity, quality of life, and the practical realities of care. Dr. Monty Powell and Dr.

Highlights From the 2026 ASCO GU Cancers SymposiumMar 5, 2026

A focused ASCO GU recap that puts bladder cancer data into clear clinical perspective.

The ASCO Daily News Podcast shapes highlights from the 2026 ASCO GU Cancer Symposium into a clear, data-forward discussion with practical clinical interest. Dr. Monty Powell and Dr.

Personalizing Treatment in Head and Neck CancersFeb 19, 2026

A clinically focused look at how circulating tumor DNA may guide strategy and surveillance in head and neck cancer.

Personalized treatment in head and neck cancer gets a focused, clinically grounded treatment as Dr. Monty Powell speaks with Dr. Ari Rosenberg about HPV-related disease, circulating tumor DNA, and the molecular signals that may shape care.

Podcasts like ASCO Daily News

Episodes

  1. 1

    'No Margin for Error': What to Know Before Implementing AI in Clinical Practice

    Hidden gem

    ASCO Daily News hosts Dr.

    Apr 16, 2026·18m·1 clip
  2. 2

    Groundbreaking Results Shift Treatment Paradigm in High-Risk Smoldering Multiple Myeloma

    Hidden gem

    Experts discuss the AQUILA trial and FDA approval of daratumumab for high-risk smoldering multiple myeloma, shifting from watch-and-wait to early treatment.

    Apr 2, 2026·20m·1 clip
  3. 3

    Navigating Therapeutic Advances in EGFR-Mutated NSCLC

    Hidden gem

    Dr.

    Mar 19, 2026·19m·1 clip
  4. 4

    Highlights From the 2026 ASCO GU Cancers Symposium

    Hidden gem

    Highlights key abstracts from the 2026 ASCO GU Cancers Symposium, focusing on bladder cancer research and patient-centered care.

    Mar 5, 2026·20m·1 clip
  5. 5

    Personalizing Treatment in Head and Neck Cancers

    Hidden gem

    ASCO Daily News hosts Dr.

    Feb 19, 2026·21m·1 clip
  6. 6

    Can Low-Dose Immunotherapy Expand Global Access to Cancer Care?

    Hidden gem

    Atul Batra says fewer than 5% of patients in India could access standard-dose pembrolizumab, prompting AIIMS New Delhi to test a lower-dose approach in the PLANET study.

    Feb 5, 2026·15m
  7. 7

    Highlights From the 2026 ASCO GI Cancers Symposium

    The DISCO trial cut futile surgeries from over 40% to about 20% using diffusion-weighted MRI for peritoneal staging.

    Jan 26, 2026·20m·1 clip
  8. 8

    Expanding Treatment Options for Breast Cancer: ADCs and Oral SERDs

    Dr.

    Jan 8, 2026·27m·1 clip
  9. 9

    What Challenges Will Oncologists Face in 2026?

    Dec 4, 2025·22m
  10. 10

    What Frontline Treatment Should Be Used in Advanced Ovarian Cancer?

    Nov 20, 2025·26m
  11. 11

    Managing Immune-Related Toxicities in Oncology

    Nov 6, 2025·15m
  12. 12

    Key Takeaways From the 2025 ASCO Quality Care Symposium

    Oct 16, 2025·17m
  13. 13

    Identifying Young BRCA Carriers With Breast Cancer: Early Detection Can Lead to Better Prognosis

    Oct 2, 2025·14m
  14. 14

    Cancer and Aging: Researching the Path to Longer, More Vibrant Lives

    Sep 18, 2025·18m
  15. 15

    Promising New Therapies in Non-Muscle Invasive Bladder Cancer

    Sep 4, 2025·18m
  16. 16

    The Gut Microbiome and Immunotherapy: Researching the Connection

    Aug 21, 2025·19m
  17. 17

    Why Are Early-Onset GI Cancers on the Rise?

    Aug 7, 2025·17m
  18. 18

    What Is Precision Palliative Care? Rethinking a Care Delivery Problem

    Jul 31, 2025·28m
  19. 19

    From Clinic to Clinical Trials: Responsible AI Integration in Oncology

    Jul 10, 2025·24m
  20. 20

    Immunotherapy at ASCO25: Drug Development, Melanoma Treatment, and More

    Jun 27, 2025·27m
  21. 21

    Innovations in GU Cancer Treatment at ASCO25

    Jun 26, 2025·30m
  22. 22

    What Lung Cancer Abstracts Stood Out at ASCO25?

    Jun 25, 2025·30m
  23. 23

    GI Cancer Research at ASCO25: Plenary Highlights and More

    Jun 24, 2025·21m
  24. 24

    Breast Cancer Research Poised to Change Practice From ASCO25

    Jun 23, 2025·32m
  25. 25

    Precision Oncology Advances in Hematologic Cancers at ASCO25

    Jun 20, 2025·18m
  26. 26

    ASCO25 Recap: CHALLENGE, DESTINY-Breast09, and More

    Jun 19, 2025·26m
  27. 27

    Day 5: Top Takeaways From ASCO25

    Jun 3, 2025·10m
  28. 28

    Day 4: Top Takeaways from ASCO25

    Jun 2, 2025·9m
  29. 29

    Day 3: Top Takeaways From ASCO25

    Jun 1, 2025·9m
  30. 30

    Day 2: Top Takeaways From ASCO25

    May 31, 2025·10m
  31. 31

    Day 1: Top Takeaways From ASCO25

    May 30, 2025·10m
  32. 32

    ASCO25 Preview: Key Research Accelerating Cancer Care

    ASCO Daily News host Dr.

    May 22, 2025·21m·1 clip
  33. 33

    Optimizing Oncology Clinical Pathways at the Point of Care

    Apr 17, 2025·27m
  34. 34

    Personalizing Lung Cancer Management With ctDNA: Where We Are and Where We Are Headed

    Apr 3, 2025·19m
  35. 35

    The Evolving Role of Precision Surgery in Gynecologic Cancers

    Mar 13, 2025·26m
  36. 36

    Emerging Therapies in Acute Myeloid Leukemia

    Mar 6, 2025·30m
  37. 37

    Practice-Informing Research Across GU Oncology: Highlights From GU25

    Dr.

    Feb 27, 2025·28m
  38. 38

    Therapeutic Advances Across GI Cancers: Highlights From GI25

    Dr.

    Feb 6, 2025·21m
  39. 39

    Advances in Adjuvant Therapy for High-Risk Early Breast Cancer With Germline Mutations

    Jan 30, 2025·20m
  40. 40

    How to Advance Cancer Care for Native Americans

    Jan 9, 2025·18m
  41. 41

    What Challenges Will Oncologists Face in 2025?

    Dr.

    Dec 5, 2024·23m
  42. 42

    A New Standard of Care for Cervical Cancer: Assessing the KEYNOTE-A18 Study

    Nov 21, 2024·14m
  43. 43

    Advances in Immunotherapy for Melanoma and Beyond

    Oct 31, 2024·18m
  44. 44

    Personalizing Locoregional Treatment for Breast Cancer

    Oct 17, 2024·19m
  45. 45

    How Are Cancer Centers Navigating IV Fluid Shortages and the Devastation of Hurricane Season?

    Oct 9, 2024·18m
  46. 46

    Key Takeaways From the 2024 ASCO Quality Care Symposium

    Dr.

    Oct 3, 2024·21m
  47. 47

    Key Takeaways From 2024 ASCO Breakthrough

    Aug 22, 2024·14m
  48. 48

    How AI Can Improve Patient Identification and Recruitment for Clinical Trials

    Aug 15, 2024·18m
  49. 49

    DESTINY-Breast06 and A-BRAVE: Advances in Breast Cancer Research

    Aug 8, 2024·15m
  50. 50

    The Risks and Benefits of Taking a Break From Cancer Treatment

    Aug 1, 2024·19m