The Nutritional Mental Health Podcast · Annika Angelo, M.S.

I Tried the World's Most Researched Mental Health Supplement - Here's How It Went + the Science Behind It

·50 min·3 clips
Host Annika interviews Taryn Fletcher, a scientist at Hardy Nutritionals, about Daily Essential Nutrients (DEN) — a broad-spectrum vitamin and mineral formula that is the world's most researched mental health supplement. The episode traces the supplement's origin to a father's desperation after losing his wife to bipolar-related suicide, explains the biochemical mechanism (cofactor saturation of enzyme pathways, mitochondrial energy production), and walks through compelling personal recovery stories across bipolar disorder, schizoaffective disorder, and the host's own ADHD and anxiety. Key research covered includes the NutroMum trial showing that DEN-exposed infants outperformed placebo and antidepressant-exposed infants on neonatal scales, and the known phenomenon of DEN potentiating psychiatric medication response — requiring supervised dose reductions.

As heard by us

A product-forward but useful look at nutrients, mood, and the lived shape of change.

The episode is a product-forward conversation about a mental health supplement, and it works best when it stays close to lived experience and day to day change.

Read the full review in PlayNext →

Why you'd press play

Press play if you want the research, the stories, and a 30-day first-hand trial in one place.

Read the full recommendation in PlayNext →
Listen to the show on