The Disappearing Spoon: a science history podcast with Sam Kean · Sam Kean, Bleav

The Birds and the Bees and the Frogs

April 15, 2025·19 min·1 clip
Hogben's improbable hypothesis that pregnant women's urine would make frogs lay eggs proved correct, creating a revolutionary non-lethal test.
This episode explores how Lancelot Hogben discovered that African clawed frogs could detect pregnancy through urine, creating the first affordable, non-lethal pregnancy test that revolutionized women's healthcare. The story traces the test's development, global impact, and unintended ecological consequences while revealing Hogben's fascinating life as a scientist and social activist.

As heard by us

A frog test becomes a clear, humane history of medicine and the world around it.

A pregnancy test built from frogs sounds like a stunt, but the piece treats it as real medicine. It traces the path from ancient seed-sprouting tests to Lancelot Hogben's African clawed frog and makes the science easy to follow without flattening the oddness.

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Why you'd press play

You want the strange history of pregnancy testing, from ancient grain sprouting to frogs and urine.

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