The Curbsiders Internal Medicine Podcast · The Curbsiders Internal Medicine Podcast

#517 DIGEST: Weight regain after weight loss medications, GLP1/GIP comparisons, valacyclovir for Alzheimer’s, and nudges to encourage deprescribing

·1 hr 6 min·5 clips

Patients regain 0.8 kg per month after stopping semaglutide, returning to baseline weight in under two years.

The Curbsiders team discusses recent medical literature, including GLP-1 agonist pipeline updates, weight regain after discontinuation, a negative Alzheimer's antiviral trial, and deprescribing high-risk medications. They explore clinical implications, insurance barriers, and patient counseling strategies in internal medicine.

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