Stranded Technologies Podcast · Infinita City

Ep. 99: A Conversation with Cremieux - How to Tell Good Science from Junk, and What’s Next in US Biotech & Deregulation

·1 hr 8 min·5 clips

He argues MMR should be mandated because measles is bad enough to justify overriding libertarian objections.

The episode opens as an informal live conversation and stays deliberately loose. The host frames Krimu as a very online figure who has shaped the discourse and says the audience is hearing him early. Krimu begins by describing himself as a bioinformatician who writes software for biology and works in healthcare. He also notes that being visible online can attract strange stalkers, so he keeps some things close to the vest. From there, the discussion moves away from biography and into public health as a systems problem. Rotary Club comes up in the context of anti-polio work, and that leads into screw worms and the long-running effort to keep them out of the United States. Krimu describes the sterilized insect barrier as a huge, recurring expense that exists because full eradication was not pursued. The point extends to polio and other infections. The host keeps pressing on why public health so often chooses partial control over elimination. Krimu answers in terms of will, arguing that the technical ability often exists but the political and institutional resolve does not. The conversation uses that example to broaden into a general critique of how societies make the wrong choices about public health. From there, the episode shifts into the boundary between real science and junk science. The guest keeps coming back to mechanism, not slogans. That same logic carries into biotech and drug development. GLP-1R becomes a focal point. Krimu argues that siRNA may be a better path to effectively creating naturally high GLP-1R levels than direct injection of GLP-1, glucagon, or GIP. He treats that approach as a mispriced modality that deserves more attention. The host lets the argument unfold with relatively little interruption. That gives the guest room to build from first principles rather than deliver a polished set of talking points. The result is a conversation that ties together public health, regulation, and frontier biotech as one connected problem. It ends with the sense that the main bottleneck is not imagination, but the institutions that decide what gets pursued.

As heard by us

A systems-minded conversation about public health, disease elimination, and biotech.

This conversation links biotech to public health in a way that feels grounded rather than abstract, moving from polio and screw worm control to the cost of keeping containment walls in place.

Read the full review in PlayNext →

Why you'd press play

You want a sharp, unscripted fireside chat about biotech, public health, and frontier-tech policy.

Read the full recommendation in PlayNext →

Listen to the show on

Apple Podcasts Spotify

Play clips from this episode More from Stranded Technologies Podcast