Naked Neuroscience, from the Naked Scientists · James Tytko

Managing multiple sclerosis

·28 min·1 clip

This episode of The Naked Scientists explores multiple sclerosis (MS) from diagnosis through to cutting-edge treatments, featuring a patient's personal account alongside expert neurologists. It covers the immunological mechanisms behind relapsing remitting and progressive MS, the landscape of disease modifying therapies, and emerging approaches including remyelination, neuroprotection, and BTK inhibitors. The episode concludes with a detailed look at the OCTOPUS multi-arm multi-stage clinical trial, designed to accelerate the search for neuroprotective treatments for progressive MS.

As heard by us

A clear, humane look at MS biology, treatment, and the trade-offs that still matter.

The episode tracks multiple sclerosis from relapses to neurodegeneration with a steady grasp of both the biology and the lived cost. It lays out how white blood cells attack myelin, how nerve signals get disrupted, and why symptoms can range from numbness and tingling to…

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Why you'd press play

If you want MS explained from relapses to neurodegeneration, start here.

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